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Acromegaly

From Wikipedia
acromegaly
rare disease, class of disease
Subclass ofhyperpituitarism, disease Edit
Health specialtyendocrinology Edit
Drug or therapy used for treatmentoctreotide, pegvisomant, bromocriptine Edit
Genetic associationAIP Edit
Comorbiditytype 2 diabetes Edit
NCI Thesaurus IDC84533 Edit
Opposite ofacromicria Edit

Acromegaly be a disorder wey dey result in excess growth of certain parts of de human body. E be caused by excess growth hormone (GH) after na de growth plates close. De initial symptom be typically enlargement of de hands den feet.[1] Der sanso be an enlargement of de forehead, jaw, den nose. Oda symptoms fi include joint pain, thickened skin, deepening of de voice, headaches, den problems plus vision.[1] Complications of de disease fi include type 2 diabetes, sleep apnea, den high blood pressure.[1]

Notable people

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  • Salvatore Baccaro (1932–1984), Italian character actor.
  • Paul Benedict (1938–2008), American actor.[2]
  • Mary Ann Bevan (1874–1933), an English woman.[3]
  • Eddie Carmel, born Oded Ha-Carmeili (1936–1972), Mandatory Palestine-born entertainer
  • Rondo Hatton (1894–1946), American journalist den actor.[4]
  • Irwin Keyes (1952–2015), American actor.[5]
  • Richard Kiel (1939–2014), actor
  • Sultan Kösen[6]
  • Neil McCarthy (1932–85), British actor.[7]
  • The Great Khali (Dalip Singh Rana), Indian professional wrestler.[8]
  • André the Giant (André Roussimoff, 1946–1993), French professional wrestler den actor
  • Maximinus Thrax, Roman emperor (c. 173, he reign 235–238)
  • The French Angel (Maurice Tillet, 1903–1954), Russian-born French professional wrestler.[9]
  • Pío Pico, de last Mexican Governor of California (1801–1894)[10][11]
  • Leonel Edmundo Rivero, Argentine tango singer, composer den impresario
  • Tony Robbins, motivational speaker[12]
  • Antônio "Bigfoot" Silva, Brazilian kickboxer den mixed martial artist.[13][14][15]
  • Carel Struycken, Dutch actor[16]
  • Nikolai Valuev, Russian politician den former professional boxer
  • Big Show (Paul Wight), American professional wrestler den actor.[17]
  • Pianist den composer Sergei Rachmaninoff (1873–1943)[18]
  • Matthew McGrory, (1973–2005) American actor[19]
  • Marjon van Iwaarden, Dutch singer[20]
  • Gheorghe Mureșan, Romanian former basketball player dem nickname The Giant
  • Jacob Grommer (1879–1933) Belarusian mathematician.[21][22]

References

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  1. 1 2 3 "Acromegaly". NIDDK. April 2012. Archived from the original on 27 August 2016. Retrieved 20 August 2016.
  2. ↑ Times Staff And Wire Reports (5 December 2008). "Paul Benedict dies at 70; actor from 'The Jeffersons' and 'Sesame Street'". Los Angeles Times. Archived from the original on 26 August 2016.
  3. ↑ "National Fairground Archive – Extracts from World's Fair, 1931–1940". The University of Sheffield. 2007. Archived from the original on 18 May 2015. Retrieved 28 July 2025.
  4. ↑ Duryea B (27 June 1999). "Floridian: In love with a monster". St Petersburg Times. Archived from the original on 8 June 2016.
  5. ↑ Dagan C (8 July 2015). "Irwin Keyes, Horror Movie Character Actor, Dies at 63". Variety. Archived from the original on 29 May 2016.
  6. ↑ "Tallest man living". Guinness World Records. Retrieved 25 September 2025.
  7. ↑ Stampede P. "Neil McCarthy". The Avengers Forever. Retrieved 29 January 2014.
  8. ↑ Harish A. "WWE Star Great Khali's Growth-Inducing Tumor Removed". ABC News. Archived from the original on 4 March 2016.
  9. ↑ Oliver G. "The French Angel was more man than monster". SLAM! Wrestling. Archived from the original on 6 July 2015.
  10. ↑ Login IS, Login J (July 2008). "Governor Pio Pico, the monster of California...no more: lessons in neuroendocrinology". Pituitary. 13 (1): 80–6. doi:10.1007/s11102-008-0127-1. PMC 2807602. PMID 18597174.
  11. ↑ Nawar RN, AbdelMannan D, Selman WR, Arafah BM (2008). "Pituitary tumor apoplexy: a review". Journal of Intensive Care Medicine. 23 (2): 75–90. doi:10.1177/0885066607312992. PMID 18372348. S2CID 34782106.
  12. ↑ Plaskin G (13 August 2013). "Playboy Interview: Tony Robbins". Playboy. Archived from the original on 2 April 2015. Retrieved 5 March 2015.
  13. ↑ "Ex-treinador de Pezão, André Benkei explica doença do lutador e afirma: 'Ele jamais colocaria a saúde em risco'". 23 December 2013.
  14. ↑ "TRT ban forces UFC headliner 'Bigfoot' Silva into surgery". 12 September 2014.
  15. ↑ "UFC title hopeful 'Bigfoot' Silva a real-life giant". USA Today.
  16. ↑ McLellan, Dennis (27 December 1992). "Shedding Light on a Rare Disease: Woman Hopes O.C. Group Will Increase Awareness of Life-Threatening Effects of Excessive-Growth Illness". Los Angeles Times.
  17. ↑ Emerson, LaTina (2011-04-02). "A giant among men".
  18. ↑ Ramachandran, Manoj; Jeffrey K Aronson (Oct 2006). "The diagnosis of art: Rachmaninov's hand span". Journal of the Royal Society of Medicine. 99 (10): 529–30. doi:10.1177/014107680609901015. PMC 1592053. PMID 17066567.
  19. ↑ "Misbehaving Pituitaries". Damn Interesting (in American English). Retrieved 16 August 2024.
  20. ↑ "Dutch Acromegaly Patient Marjon van Iwaarden Shares Her Story". Acromegaly Support - Rare Disease Awareness, Education, and Support (in American English). 27 May 2020. Retrieved 16 August 2024.
  21. ↑ Gutfreund, Hanoch and Jürgen Renn. The Formative Years of Relativity: The History and Meaning of Einstein's Princeton Lectures. Princeton University Press. 2017. Page 393.
  22. ↑ Denis, Brian. Einstein: A Life. John Wiley & Sons. 1997. Page 169.
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