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Alopecia areata

From Wikipedia
alopecia areata
class of disease, signs den symptoms
Subclass ofalopecia, Autoimmune disease, autoimmune skin disease Edit
Health specialtydermatology Edit
Genetic associationSTX17, IL2RA, IKZF4, HR Edit
WordLift URLhttp://data.medicalrecords.com/medicalrecords/healthwise/alopecia_areata_2 Edit
ICD-9-CM704.01 Edit
ICPC 2 IDS23 Edit

Alopecia areata (AA), dem sanso know as spot baldness, be a condition insyd wich hair be lost from sam anaa all areas of de body.[1][2] E often dey result in a few bald spots on de scalp, each about de size of a coin.[3] Psychological stress den illness be possible factors in bringing on alopecia areata insyd individuals at risk, buh insyd chaw cases der be no obvious trigger.[3] People generally be otherwise healthy.[3] Insyd a few cases, all de hair on de scalp be lost (alopecia totalis), anaa all body hair be lost (alopecia universalis). Hair loss fi be permanent anaa temporary.[2][3]

Alopecia areata be believed to be an autoimmune disease wey dey result from a breach insyd de immune privilege of de hair follicles.[1][4] Risk factors dey include a family history of de condition.[3] Among identical twins, if one be affected, de oda get about a 50% chance of being affected.[3] De underlying mechanism dey involve failure by de body to recognize ein own cells, plus subsequent immune-mediated destruction of de hair follicle.[3]

No cure for de condition be known.[3] Sam treatments, particularly triamcinolone injections den 5% minoxidil topical creams,[5][6] be effective in speeding hair regrowth.[2][3] Sunscreen, head coverings to protect from cold den sun, den glasses, if de eyelashes be missing, sanso be recommended.[3] In more dan 50% of cases of sudden-onset localized "patchy" disease, hair regrow within a year.[3][7][8] Insyd patients plus one anaa two patches per, dis one-year recovery go occur insyd up to 80%.[9][10] However, chaw people go get more dan one episode over de course of a lifetime.[8] Insyd chaw patients, hair loss den regrowth dey occur simultaneously over de course of several years.[3] Among those insyd whom all body hair be lost, fewer dan 10% recover.[11]

About 0.15% of people be affected at any one time, den 2% of people be affected at sam point in time.[3][11] Onset usually be insyd kiddie time.[3] Females be affected at higher rates dan males.[12]

Notable people

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  • Joey Logano, NASCAR driver
  • Kevin Bull obstacle athlete,[13]
  • Peter Dutton, politician[14]
  • Ayanna Pressley politician,[15]
  • Peniel Shin, K-pop singer of BtoB,[16]
  • Christopher Reeve, actor[17]
  • Anthony Carrigan, actor[18]
  • Greg Grunberg, actor
  • Alan Fletcher actor,[19]
  • Jada Pinkett Smith, actress[20]
  • May Calamawy, actress[21] and
  • Lili Reinhart, actress[22]
  • Molly Tuttle be a spokesperson give de National Alopecia Areata Foundation.

References

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  1. 1 2 Erjavec SO, Gelfman S, Abdelaziz AR, Lee EY, Monga I, Alkelai A, Ionita-Laza I, Petukhova L, Christiano AM (February 2022). "Whole exome sequencing in Alopecia Areata identifies rare variants in KRT82". Nature Communications. 13 (1) 800. Bibcode:2022NatCo..13..800E. doi:10.1038/s41467-022-28343-3. PMC 8831607. PMID 35145093.
  2. 1 2 3 "Alopecia Areata - Symptoms, Causes, Treatment | NORD" (in American English). Retrieved 2026-04-09.
  3. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 Fleming R (May 2016). "Questions and Answers About Alopecia Areata". NIAMS. Archived from the original on 4 July 2017. Retrieved 10 July 2017.
  4. ↑ Rajabi F, Drake LA, Senna MM, Rezaei N (November 2018). "Alopecia areata: a review of disease pathogenesis". The British Journal of Dermatology. 179 (5): 1033–1048. doi:10.1111/bjd.16808. PMID 29791718. S2CID 43940520.
  5. ↑ Yee BE, Tong Y, Goldenberg A, Hata T (April 2020). "Efficacy of different concentrations of intralesional triamcinolone acetonide for alopecia areata: A systematic review and meta-analysis". Journal of the American Academy of Dermatology. 82 (4): 1018–1021. doi:10.1016/j.jaad.2019.11.066. PMID 31843657. S2CID 209389315.
  6. ↑ Freire PC, Riera R, Martimbianco AL, Petri V, Atallah AN (September 2019). "Minoxidil for patchy alopecia areata: systematic review and meta-analysis". Journal of the European Academy of Dermatology and Venereology. 33 (9): 1792–1799. doi:10.1111/jdv.15545. PMID 30835901. S2CID 73460786.
  7. ↑ Paggioli I, Moss J (December 2022). "Alopecia Areata: Case report and review of pathophysiology and treatment with Jak inhibitors". Journal of Autoimmunity. 133 102926. doi:10.1016/j.jaut.2022.102926. PMID 36335798. S2CID 253320808.
  8. 1 2 Alkhalifah A, Alsantali A, Wang E, McElwee KJ, Shapiro J (February 2010). "Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis". Journal of the American Academy of Dermatology. 62 (2): 177–88, quiz 189–90. doi:10.1016/j.jaad.2009.10.032. PMID 20115945.
  9. ↑ Spano F, Donovan JC (September 2015). "Alopecia areata: Part 1: pathogenesis, diagnosis, and prognosis". Canadian Family Physician. 61 (9): 751–755. PMC 4569104. PMID 26371097.
  10. ↑ Mounsey AL, Reed SW (August 2009). "Diagnosing and treating hair loss". American Family Physician. 80 (4): 356–362. PMID 19678603. Archived from the original on 16 November 2022. Retrieved 16 November 2022.
  11. 1 2 Beigi PK (2018). Alopecia Areata: A Clinician's Guide. Springer. p. 14. ISBN 978-3-319-72134-7. Archived from the original on 14 January 2023. Retrieved 1 October 2020.
  12. ↑ Lundin M, Chawa S, Sachdev A, Bhanusali D, Seiffert-Sinha K, Sinha AA (April 2014). "Gender differences in alopecia areata". Journal of Drugs in Dermatology. 13 (4): 409–413. PMID 24719059.
  13. ↑ "American alopecia ninja attacks awareness". Dermatology Times. 8 July 2016. Archived from the original on 27 January 2021. Retrieved 23 February 2021.
  14. ↑ Maiden S (27 May 2022). "Peter Dutton officially launches Liberal leadership campaign, reveals skin condition is alopecia". news.com.au. Archived from the original on 30 May 2022. Retrieved 5 June 2022.
  15. ↑ "Exclusive: Rep. Ayanna Pressley Reveals Beautiful Bald Head and Discusses Alopecia for the First Time". The Glow Up. 16 January 2020. Archived from the original on 16 January 2020. Retrieved 13 January 2021.
  16. ↑ Kang Hee-jung (15 November 2016). ""탈모인 파이팅!" 프니엘, '안녕하세요' 출연 후기 게재" ["Fighting hair loss!" Peniel's review of'Hello' appeared]. News1 (in Korean). Archived from the original on 17 November 2020. Retrieved 6 May 2022.
  17. ↑ Groopman J (2 November 2003). "The Reeve Effect". The New Yorker.
  18. ↑ Nedd A, Kibblesmith D, Bertozzi D (27 February 2015). "Gotham's Anthony Carrigan Talks Acting, Alopecia, And Learning To Love His Look". BuzzFeed. Archived from the original on 25 September 2018. Retrieved 17 August 2018.
  19. ↑ Knox D (20 May 2022). "Alan Fletcher reveals alopecia to fans". TV Tonight. Archived from the original on 8 June 2022. Retrieved 8 June 2022.
  20. ↑ Bellamy C (7 January 2022). "How Jada Pinkett Smith is uplifting Black women with alopecia". NBCBLK. Archived from the original on 28 March 2022. Retrieved 28 March 2022.
  21. ↑ Calamawy M (11 June 2020). "Sharing My Alopecia Helped Me Set New Expectations for Myself". Glamour. Archived from the original on 5 June 2021. Retrieved 5 June 2021.
  22. ↑ "Lili Reinhart Reveals She Was Diagnosed With Alopecia". Hollywood Reporter. 31 January 2024.
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