Jump to content

Amnesia

From Wikipedia
amnesia
class of disease, signs den symptoms
Subclass ofcognitive disorder, memory disorder, psychopathological syndrome, disease Edit
Health specialtypsychiatry, neurology Edit
ICD-9-CM780.9, 780.93, 294.0 Edit
ICPC 2 IDP20 Edit
NCI Thesaurus IDC2867 Edit

Amnesia be a deficit insyd memory wey brain damage anaa brain diseases cause,[1] buh e sanso fi be temporarily caused by de use of various sedative den hypnotic drugs. De memory either fi be wholly anaa partially lost secof de extent of damage wey be caused.[2]

Der be two main types of amnesia:

  • Image of retrograde amnesia
    Retrograde amnesia be de inability to remember information wey be acquired before a particular date, usually de date of an accident anaa operation.[3] Insyd sam cases, de memory loss fi extend back decades, while insyd oda cases, people fi loose a few months of memory per.
  • Anterograde amnesia be de inability to transfer new information from de short-term store into de long-term store. People plus anterograde amnesia no dey kai things for long periods of time.

Dese two types no be mutually exclusive; both sanso fi occur simultaneously.[4]

In addition to retrograde den anterograde amnesia, oda recognized forms dey include transient global amnesia, a temporary loss of memory wey dey cam on suddenly; dissociative amnesia, wich be linked to emotional stress den dey involve inability to recall personal experiences; childhood amnesia, wey dey refer to early life memory loss wey be common across individuals; den post-traumatic amnesia, wich fi follow a head injury den dey involve confusion den memory impairment for events around de time of de trauma.[5]

Case studies sanso dey show say amnesia typically be associated plus damage to de medial temporal lobe. In addition, specific areas of de hippocampus (de CA1 region) be involved plus memory. Research sanso show say wen areas of de diencephalon be damaged, amnesia fi occur. Recent studies show a correlation between deficiency of RbAp48 protein den memory loss. Scientists able be to find say mice plus damaged memory get a lower level of RbAp48 protein dem compare to normal, healthy mice.[6][7] Insyd people plus amnesia, de ability to recall immediate information still be retained,[8][9][10]

wey dem still fi be able to form new memories. However, a severe reduction insyd de ability to learn new material den retrieve old information fi be observed. People fi learn new procedural knowledge. In addition, priming (both perceptual den conceptual) fi assist amnesiacs insyd de learning of fresh non-declarative knowledge.[1] Individuals plus amnesia sanso retain substantial intellectual, linguistic, den social skills despite profound impairments insyd de ability to recall specific information dem encounter in prior learning episodes.[11][12][13]

De term be Ancient Greek 'forgetfulness'; from ἀ- (a-) 'widout' den μνήσις (mnesis) 'memory'.

References

[edit | edit source]
  1. 1 2 Gazzaniga, M., Ivry, R., & Mangun, G. (2009) Cognitive Neuroscience: The biology of the mind. New York: W.W. Norton & Company.
  2. "Amnesia." The Gale Encyclopedia of Science. Ed. K. Lee Lerner and Brenda Wilmoth Lerner. 4th ed. Vol. 1. Detroit: Gale, 2008. 182–184. Gale Virtual Reference Library.
  3. Schacter, Daniel. L "Psychology"
  4. David X. Cifu; Henry L. Lew (2013-09-10). Handbook of Polytrauma Care and Rehabilitation (in English). Demos Medical Publishing. ISBN 978-1-61705-100-5.
  5. Short, Shari (2024-08-14). "What Are the 4 Types of Amnesia?". Aloha Counseling LLC (in American English). Retrieved 2026-02-11.
  6. Pavlopoulos, Elias; Jones, Sidonie; Kosmidis, Stylianos; Close, Maggie; Kim, Carla; Kovalerchik, Olga; Small, Scott A.; Kandel, Eric R. (2013-08-28). "Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48". Science Translational Medicine. 5 (200): 200ra115. doi:10.1126/scitranslmed.3006373. ISSN 1946-6242. PMC 4940031. PMID 23986399.
  7. Kosmidis, Stylianos; Polyzos, Alexandros; Harvey, Lucas; Youssef, Mary; Denny, Christine A.; Dranovsky, Alex; Kandel, Eric R. (2018-10-23). "RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss". Cell Reports (in English). 25 (4): 959–973.e6. doi:10.1016/j.celrep.2018.09.077. ISSN 2211-1247. PMC 7725275. PMID 30355501.
  8. Dewar, Michaela; Della Sala, Sergio; Beschin, Nicoletta; Cowan, Nelson (2010). "Profound retroactive interference in anterograde amnesia: What interferes?". Neuropsychology (in English). 24 (3): 357–367. doi:10.1037/a0018207. ISSN 1931-1559. PMC 2864945. PMID 20438213.
  9. Baddeley, Alan; Wilson, Barbara A. (April 2002). "Prose recall and amnesia: implications for the structure of working memory". Neuropsychologia (in English). 40 (10): 1737–1743. doi:10.1016/S0028-3932(01)00146-4. PMID 11992661. S2CID 22404837 via Elsevier Science Direct.
  10. Benson, D. Frank (1978). "Amnesia". Southern Medical Journal. 71 (10): 1221–1227. doi:10.1097/00007611-197810000-00011. PMID 360401. S2CID 220554752.
  11. LS., Cermak (1984). The episodic-semantic distinction in amnesia. New York: Guilford Press. p. 55.
  12. M, Kinsbourne (1975). Short-term memory processes and the amnesiac syndrome. New York: Academic. pp. 258–91.
  13. H, Weingartner (1983). Forms of cognitive failure. Sc alzheimerience. pp. 221:380–2.
[edit | edit source]