Amoxicillin
| Subclass of | penicillin, carboxylic acid  |
|---|---|
| Get use | Medication |
| Stereoisomer of | L-amoxicillin |
| Chemical formula | C₁₆H₁₉N₃O₅S |
| Canonical SMILES | CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)C(=O)O)C |
| Isomeric SMILES | CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)C(=O)O)C |
| Active ingredient in | Amoxil, Moxatag |
| Found insyd taxon | Arundo donax, Guignardia |
| Route of administration | oral administration, intravenous infusion and defusion |
| Pregnancy category | Australian pregnancy category A, US pregnancy category B |
| LiverTox likelihood score | LiverTox toxicity likelihood category B |
| Subject has role | enzyme inhibitor, antibiotic, essential medicine, bactericide |
| WHO Aware Classification | access |
| NCI Thesaurus ID | C237 |
Amoxicillin be an antibiotic medication wey dey belong to de aminopenicillin class of de penicillin family. Dem dey use de drug to treat bacterial infections[1] such as middle ear infection, strep throat, pneumonia, skin infections, odontogenic infections, den urinary tract infections.[1] Dem dey take am orally (dem swallow by mouth), anaa less commonly by either intramuscular injection anaa by an IV bolus injection, wich be a relatively quick intravenous injection wey dey last from a couple of seconds to a few minutes.[1][2]
Common adverse effects dey include nausea den rash.[1] E sanso fi increase de risk of yeast infections, den wen dem use am in combination plus clavulanic acid, diarrhea.[3] Dem for no use am insyd those wey be allergic to penicillin.[1] While usable insyd those plus kidney problems, de dose fi hia make dem decrease am.[1] Ein use insyd pregnancy den breastfeeding no appear e be harmful.[1] Amoxicillin dey insyd de β-lactam family of antibiotics.[1]
Na dem discover amoxicillin insyd 1958 wey na e cam into medical use insyd 1972.[4][5] Na dem approve amoxil for medical use insyd de United States insyd 1974,[6][7] den insyd de United Kingdom insyd 1977. E dey on de World Health Organization's List of Essential Medicines.[8] E be one of de most commonly prescribed antibiotics insyd kiddies.[9] Amoxicillin be available as a generic medication.[1] Insyd 2023, na e be de 23rd most commonly prescribed medication insyd de United States, plus more dan 23 million prescriptions.[10][11]
References
[edit | edit source]- 1 2 3 4 5 6 7 8 9 "Amoxicillin". Drugs.com, The American Society of Health-System Pharmacists. 3 January 2022. Archived from the original on 24 November 2022. Retrieved 24 November 2022.
- ↑ "Amoxicillin Sodium for Injection". EMC. 10 February 2016. Archived from the original on 27 October 2016. Retrieved 26 October 2016.
- ↑ Gillies M, Ranakusuma A, Hoffmann T, Thorning S, McGuire T, Glasziou P, Del Mar C (January 2016). "Common harms from amoxicillin: a systematic review and meta-analysis of randomized placebo-controlled trials for any indication". CMAJ. 187 (1): E21 – E31. doi:10.1503/cmaj.140848. PMC 4284189. PMID 25404399.
- ↑ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 490. ISBN 978-3-527-60749-5. Archived from the original on 8 September 2017.
- ↑ Roy J (2012). An introduction to pharmaceutical sciences production, chemistry, techniques and technology. Cambridge: Woodhead Pub. p. 239. ISBN 978-1-908818-04-1. Archived from the original on 8 September 2017.
- ↑ "Drugs@FDA: FDA-Approved Drugs". www.accessdata.fda.gov (in English). Archived from the original on 2022-10-09. Retrieved 2026-01-09.
- ↑ "Drugs@FDA: FDA-Approved Drugs". www.accessdata.fda.gov (in English). Archived from the original on 2022-10-09. Retrieved 2026-01-09.
- ↑ World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.
- ↑ Kelly D (2008). Diseases of the liver and biliary system in children (3 ed.). Chichester, UK: Wiley-Blackwell. p. 217. ISBN 978-1-4443-0054-3. Archived from the original on 8 September 2017.
- ↑ "Top 300 of 2023". ClinCalc. Archived from the original on 12 August 2025. Retrieved 12 August 2025.
- ↑ "Amoxicillin Drug Usage Statistics, United States, 2014 - 2023". ClinCalc. Retrieved 12 August 2025.
External links
[edit | edit source]
- Neal MJ (2002). Medical Pharmacology at a Glance (4th ed.). Oxford: Blackwell Science. ISBN 978-0-632-05244-8.