Anencephaly

anencephaly

class of disease

Subclass of	nervous system malformations, disease
Health specialty	medical genetics
Genetic association	TRIM36
ICD-9-CM	740.0
NCI Thesaurus ID	C84560

Anencephaly be de absence of a major portion of de brain, skull, den scalp wey dey occur during embryonic development. E be a cephalic disorder wey dey result from a neural tube defect wey dey occur wen de rostral (head) end of de neural tube fail to close, usually between de 23rd den 26th day following conception. Strictly speaking, de Greek term dey translate as "widout a brain", buh e be accepted say kiddies dem born plus dis disorder usually lack a telencephalon per, de largest part of de brain wey dey consist mainly of de cerebral hemispheres, wey dey include de neocortex, wich be responsible give cognition. De remaining structure usually be covered per by a thin layer of membrane—skin, bone, meninges, etc., all be lacking. Plus very few exceptions, infants plus dis disorder no dey survive longer dan a few hours anaa days after birth.

Anencephaly be a severe neural tube defect dem typically consider incompatible plus prolonged postnatal survival, den as such, surgical intervention no be commonly indicated.