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Aripiprazole

From Wikipedia
aripiprazole
type of chemical entity
Subclass ofheterocyclic compound Edit
Get useMedication Edit
Stylized nameARIPiprazole Edit
Chemical formulaC₂₃H₂₇Cl₂N₃O₂ Edit
Canonical SMILESC1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl Edit
World Health Organisation international non-proprietary namearipiprazole Edit
Legal status (medicine)boxed warning Edit
Pregnancy categoryAustralian pregnancy category B3, US pregnancy category C Edit
LiverTox likelihood scoreLiverTox toxicity likelihood category E Edit
Subject has roleantipsychotics, atypical antipsychotic Edit

Aripiprazole, dem sell under de brand name Abilify, Aripiprex, Ariply among odas, be an atypical antipsychotic[1] dem primarily use insyd de treatment of schizophrenia, bipolar disorder, den irritability dem associate plus autism spectrum disorder;[1] oda uses dey include as an add-on treatment for major depressive disorder den tic disorders.[1] Dem dey take aripiprazole by mouth anaa via injection into a muscle.[1]

Common side effects dey include restlessness, insomnia, transient weight gain, nausea, vomiting, constipation, dizziness, den mild sedation.[1] Serious side effects fi include neuroleptic malignant syndrome, tardive dyskinesia, den anaphylaxis.[1] E no be recommended give older people plus dementia-related psychosis secof an increased risk of death.[1] Insyd pregnancy, der be evidence of possible harm to de fetus.[1][2] E no be recommended insyd women wey be breastfeeding.[1] E no be very well studied insyd people younger dan 18 years old.[1]

Na dem approve aripiprazole for medical use insyd de United States insyd 2002.[1] E be available as a generic medication.[3] Insyd 2023, na e be de 95th most commonly prescribed medication insyd de United States, plus more dan 7 million prescriptions.[4][5] E be on de World Health Organization's List of Essential Medicines.[6]

References

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  1. 1 2 3 4 5 6 7 8 9 10 11 "Aripiprazole (Monograph)". Drugs.com. American Society of Health-System Pharmacists. Archived from the original on 26 November 2020. Retrieved 26 February 2019.
  2. ↑ "Prescribing medicines in pregnancy database". tga.gov.au. Therapeutic Goods Administration, Government of Australia. 3 March 2014. Archived from the original on 8 April 2014. Retrieved 22 April 2014.
  3. ↑ British national formulary: BNF 76 (76th ed.). Pharmaceutical Press. 2018. p. 392. ISBN 978-0-85711-338-2.
  4. ↑ "The Top 300 of 2023". clincalc.com. Archived from the original on 12 August 2025. Retrieved 13 August 2025.
  5. ↑ "Aripiprazole - Drug Usage Statistics, ClinCalc DrugStats Database". clincalc.com. Retrieved 13 August 2025.
  6. ↑ The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. 2023. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.

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