Breast cancer
| Subclass of | thoracic cancer, breast disease, breast neoplasm, disease |
|---|---|
| Facet give | women's health |
| Studied by | breast cancer research |
| Health specialty | oncology |
| Medical examination | MammaPrint |
| Anatomical location | female breast |
| Risk factor | smoking |
| Handled, mitigated, or managed by | breast cancer management |
| ICPC 2 ID | X76 |
| Criterion used | transforming growth factor |
Breast cancer be a cancer wey dey develop from breast tissue.[1] Signs of breast cancer fi include: a lump insyd de breast, a change insyd breast shape, dimpling of de skin, milk rejection, fluid dey cam from de nipple, a newly inverted nipple, anaa a red anaa scaly patch of skin.[2] Insyd those plus distant spread of de disease, der fi be bone pain, swollen lymph nodes, shortness of breath, anaa yellow skin.[3]
Risk factors for developing breast cancer dey include obesity, a lack of physical exercise, alcohol consumption, hormone replacement therapy during menopause, ionizing radiation, an early age at first menstruation, having kiddies late insyd life (anaa not at all), older age, having a prior history of breast cancer, den a family history of breast cancer.[2][4][5] About five to ten percent of cases be de result of an inherited genetic predisposition,[2] wey dey include BRCA mutations among odas.[2] Breast cancer most commonly dey develop insyd cells from de lining of milk ducts den de lobules wey supply dese ducts plus milk.[2] Cancers wey dey develop from de ducts be known as ductal carcinomas, while those wey dey develope from lobules be known as lobular carcinomas.[2] Der be more dan 18 oda sub-types of breast cancer.[4] De diagnosis of breast cancer be confirmed by taking a biopsy of de concerning tissue.[2] Once dem make de diagnosis, further tests be carried out to determine if de cancer spread beyond de breast den wich treatments be most likely to be effective.[2]
Breast cancer screening fi be instrumental, given say de size of a breast cancer den ein spread be among de most critical factors in predicting de prognosis of de disease. Breast cancers dem find during screening typically be smaller den less likely to have spread outsyd de breast.[6] Training health workers make dem do clinical breast examination fi get potential to detect breast cancer at an early stage.[7] A 2013 Cochrane review find say na e be unclear whether mammographic screening dey do more harm dan good, in dat a large proportion of women wey test positive turn out dem no get de disease.[8] A 2009 review for de US Preventive Services Task Force find evidence of benefit insyd those 40 to 70 years of age,[9] den de organization dey recommend screening every two years insyd women ages 50 to 74.[10]
De medications tamoxifen anaa raloxifene fi be used in an effort to prevent breast cancer insyd those wey be at high risk of developing am.[4] Surgical removal of both breasts be anoda preventive measure insyd sam high risk women.[4] Insyd those wey be diagnosed plus cancer, several treatments fi be used, wey dey include surgery, radiation therapy, chemotherapy, hormonal therapy, den targeted therapy.[2] Types of surgery dey vary from breast-conserving surgery to mastectomy.[11] Breast reconstruction fi take place at de time of surgery anaa at a later date.[11] Insyd those in whom de cancer spread to oda parts of de body, treatments be mostly aimed at improving quality of life den comfort.[11]
Outcomes give breast cancer dey vary dey depend on de cancer type, de extent of disease, den de person ein age.[11] De five-year survival rates insyd United States den insyd de UK be over 90%.[12][13] In developing countries, five-year survival rates be lower.[4] Worldwide, breast cancer be de leading type of cancer insyd women, wey dey account for 25% of all cases.[14] Insyd 2018, e result in two million new cases den 627,000 deaths.[15] E be more common insyd developed countries,[4] wey be more dan 100 times more common insyd women dan insyd men.[16][17]
References
[edit | edit source]- ↑ "Breast Cancer". NCI. January 1980. Archived from the original on 25 June 2014. Retrieved 29 June 2014.
- 1 2 3 4 5 6 7 8 9 "Breast Cancer Treatment (PDQ)". NCI. 23 May 2014. Archived from the original on 5 July 2014. Retrieved 29 June 2014.
- ↑ Saunders C, Jassal S (2009). Breast cancer (1. ed.). Oxford: Oxford University Press. p. Chapter 13. ISBN 978-0-19-955869-8. Archived from the original on 25 October 2015.
- 1 2 3 4 5 6 World Cancer Report 2014. World Health Organization. 2014. pp. Chapter 5.2. ISBN 978-92-832-0429-9.
- ↑ Fakhri N, Chad MA, Lahkim M, Houari A, Dehbi H, Belmouden A, El Kadmiri N (September 2022). "Risk factors for breast cancer in women: an update review". Medical Oncology. 39 (12) 197. doi:10.1007/s12032-022-01804-x. PMID 36071255.
- ↑ American Cancer Society (9 September 2024). "American Cancer Society Recommendations for the Early Detection of Breast Cancer". American Cancer Society. Retrieved 26 September 2024.
- ↑ Sayed, Shahin; Ngugi, Anthony K; Nwosu, Nicole; Mutebi, Miriam C; Ochieng, Powell; Mwenda, Aruyaru S; Salam, Rehana A (18 April 2023). Cochrane Breast Cancer Group (ed.). "Training health workers in clinical breast examination for early detection of breast cancer in low- and middle-income countries". Cochrane Database of Systematic Reviews (in English). 2023 (4) CD012515. doi:10.1002/14651858.CD012515.pub2. PMC 10122521. PMID 37070783.
- ↑ Gøtzsche PC, Jørgensen KJ (June 2013). "Screening for breast cancer with mammography". The Cochrane Database of Systematic Reviews. 2013 (6) CD001877. doi:10.1002/14651858.CD001877.pub5. PMC 6464778. PMID 23737396.
- ↑ Nelson HD, Tyne K, Naik A, Bougatsos C, Chan B, Nygren P, Humphrey L (November 2009). "Screening for Breast Cancer: Systematic Evidence Review Update for the US Preventive Services Task Force [Internet]". U.S. Preventive Services Task Force Evidence Syntheses. Rockville, MD: Agency for Healthcare Research and Quality. PMID 20722173. Report No.: 10-05142-EF-1.
- ↑ Siu AL (February 2016). "Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement". Annals of Internal Medicine. 164 (4): 279–96. doi:10.7326/M15-2886. PMID 26757170.
- 1 2 3 4 "Breast Cancer Treatment (PDQ)". NCI. 26 June 2014. Archived from the original on 5 July 2014. Retrieved 29 June 2014.
- ↑ "SEER Stat Fact Sheets: Breast Cancer". NCI. Retrieved 8 January 2026.
{{cite web}}: CS1 maint: url-status (link) - ↑ "Survival for breast cancer". www.cancerresearchuk.org (in English). Retrieved 2026-01-08.
- ↑ World Cancer Report 2014. World Health Organization. 2014. pp. Chapter 1.1. ISBN 978-92-832-0429-9.
- ↑ Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (November 2018). "Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries". CA: A Cancer Journal for Clinicians. 68 (6): 394–424. doi:10.3322/caac.21492. PMID 30207593.
- ↑ "World Cancer Report" (PDF). International Agency for Research on Cancer. 2008. Archived from the original (PDF) on 20 July 2011. Retrieved 26 February 2011.
- ↑ "Male Breast Cancer Treatment". Cancer.gov. 2014. Archived from the original on 4 July 2014. Retrieved 29 June 2014.