Ceftazidime
| Subclass of | cephalosporin antibiotic  |
|---|---|
| Get use | Medication |
| Stylized name | cefTAZidime |
| Stereoisomer of | (E)-ceftazidime |
| Chemical formula | C₂₂H₂₂N₆O₇S₂ |
| Canonical SMILES | CC(C)(C(=O)O)ON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-] |
| Isomeric SMILES | CC(C)(C(=O)O)O/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-] |
| Active ingredient in | Fortaz, Tazicef |
| World Health Organisation international non-proprietary name | ceftazidime |
| Found insyd taxon | Psathyrella candolleana, Myrothecium |
| Legal status (medicine) | boxed warning |
| Pregnancy category | Australian pregnancy category B1, US pregnancy category B |
| Subject has role | enzyme inhibitor, antibiotic, essential medicine, bactericide |
| WHO Aware Classification | watch |
Ceftazidime, dem sell under de brand name Fortaz among odas, be a third-generation cephalosporin antibiotic useful for de treatment of a number of bacterial infections.[1][2] Specifically dem dey use am for joint infections, meningitis, pneumonia, sepsis, urinary tract infections, malignant otitis externa, Pseudomonas aeruginosa infection, den vibrio infection.[1] Dem dey give am by injection into a vein, muscle, anaa eye.[1][3]
Common side effects dey include nausea, allergic reactions, den pain at de site of injection.[1] Oda side effects fi include Clostridioides difficile diarrhea.[1] Dem no recommend am insyd people wey na dem previous get anaphylaxis to a penicillin.[1] Ein use be relatively safe during pregnancy den breastfeeding.[4] E dey insyd de third-generation cephalosporin family of medications wey e dey work by interfering plus de bacteria ein cell wall.[1]
Na dem patent ceftazidime insyd 1978 wey e cam into commercial use insyd 1984.[5] E dey on de World Health Organization's List of Essential Medicines.[6] Ceftazidime be available as a generic medication.[1]
References
[edit | edit source]- 1 2 3 4 5 6 7 8 "Ceftazidime". The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.
- ↑ Katzung B (2019). Basic & Clinical Pharmacology (14th ed.). McGraw Hill. p. 803. ISBN 978-1-259-64115-2.
- ↑ Kamjoo S. "Intravitreal Injections". EyeWiki. American Academy of Ophthalmology. Archived from the original on 5 March 2021. Retrieved 12 January 2020.
- ↑ Hamilton R (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 87. ISBN 9781284057560.
- ↑ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 495. ISBN 9783527607495. Archived from the original on 2016-12-20.
- ↑ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
External links
[edit | edit source]
- "Ceftazidime". Drug Information Portal. U.S. National Library of Medicine. Archived from the original on January 23, 2017.