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Citalopram

From Wikipedia
(RS)-citalopram
group of stereoisomers
Subclass ofbenzodihydrofuran, Medication, nitrile, organofluorine, tertiary amine Edit
Stylized nameCeleXA Edit
Chemical formulaC₂₀H₂₁FN₂O Edit
Canonical SMILESCN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F Edit
Active ingredient inCelexa Edit
World Health Organisation international non-proprietary namecitalopram Edit
Physically dey interact plussolute carrier family 6 member 4 Edit
Legal status (medicine)boxed warning Edit
Pregnancy categoryUS pregnancy category C Edit
Subject has roleselective serotonin reuptake inhibitor, second-generation antidepressive agents Edit

Citalopram, dem sell under de brand name Celexa among odas, be an antidepressant of de selective serotonin reuptake inhibitor (SSRI) class.[1][2] E be used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, den social phobia.[1] De antidepressant effects fi take one to four weeks to occur.[1] E be typically taken orally (dem swallow by mouth).[1][2] Insyd sam European countries, e sam times be given intravenously (dem inject into a vein) to initiate treatment, before switching to de oral route of administration for continuation of treatment.[3] E sanso be used intravenously insyd oda parts of de world insyd sam oda circumstances.[4][5]

Common side effects dey include nausea, trouble sleeping, sexual problems, shakiness, feeling tired, den sweating.[1] Insyd sam patients, sexual dysfunction fi persist even after de drug be discontinued, a condition dem know as post-SSRI sexual dysfunction; regulatory agencies wey dey include de European Medicines Agency den Health Canada recommend say citalopram ein product labeling warn of dis risk.[6][7] Serious side effects dey include an increased risk of suicide insyd those under de age of 25, serotonin syndrome, glaucoma, den QT prolongation.[1]

Na dem approve citalopram for medical use insyd de United States insyd 1998.[1] E dey on de World Health Organization's List of Essential Medicines.[8] E be available as a generic medication.[9] Insyd 2023, e be de 43rd most commonly prescribed medication insyd de United States, plus more dan 14 million prescriptions.[10][11]

Society den culture

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Brand names

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Citalopram be sold under dese brand names:

  • Akarin (Denmark, Nycomed)
  • C Pram S (India)
  • Celapram (Australia,[12] New Zealand),
  • Celexa (U.S. and Canada, Forest Laboratories, Inc.)
  • Celica (Australia)[12]
  • Ciazil (Australia,[12] New Zealand)
  • Cilate (South Africa)
  • Cilift (South Africa)
  • Cipram (Denmark, Turkey, H. Lundbeck A/S)
  • Cipramil (Australia,[12] Brazil, Belgium, Chile, Finland, Germany, Netherlands, Iceland, Ireland, Israel, New Zealand, Norway, Russia, South Africa, Sweden, United Kingdom)
  • Cipraned, Cinapen (Greece)
  • Ciprapine (Ireland)
  • Ciprotan (Ireland)
  • Citabax, Citaxin (Poland)
  • Cital (Poland)
  • Citalec (Czech Republic, Slovakia)
  • Citalex (Iran, Serbia)
  • Citalo (Australia,[12] Egypt, Pakistan)
  • Citalopram (Canada, Denmark, Finland, Germany, Ireland, The Netherlands, New Zealand, Spain, Sweden, Switzerland, United Kingdom, U.S.)
  • Citol (Russia, Turkey)
  • Citox (Mexico)
  • Citrol (Europe and Australia)[12]
  • Citta (Brazil)
  • Dalsan (Eastern Europe)
  • Denyl (Brazil)
  • Depram (Egypt)[13][14]
  • Elopram (Italy)
  • Estar (Pakistan)
  • Humorup (Argentina)
  • Humorap (Peru, Bolivia)
  • Lopraxer (Greece)[15]
  • Oropram (Iceland, Actavis),
  • Opra (Russia)
  • Pram (Russia)
  • Pramcit (Pakistan)
  • Procimax (Brazil)
  • Recital (Israel, Thrima Inc. for Unipharm Ltd.)
  • Sepram (Finland)
  • Seropram (various European countries, including the Czech Republic)
  • Szetalo (India)
  • Talam (Europe and Australia)[12]
  • Temperax (Argentina, Chile, Peru)
  • Vodelax (Turkey)
  • Zentius (South America, by Roemmers and Recalcine)
  • Zetalo (India)
  • Cipratal (Kuwait, GCC)
  • Zylotex (Portugal)[16]

References

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  1. 1 2 3 4 5 6 7 "Citalopram Hydrobromide Monograph for Professionals". Drugs.com. AHFS. Archived from the original on 23 December 2018. Retrieved 23 December 2018.
  2. 1 2 "DailyMed - CELEXA- citalopram tablet, film coated". dailymed.nlm.nih.gov. Retrieved 2026-05-16.
  3. ↑ Kasper, S.; Müller-Spahn, F. (June 2002). "Intravenous antidepressant treatment: focus on citalopram". European Archives of Psychiatry and Clinical Neuroscience. 252 (3): 105–109. doi:10.1007/s00406-002-0363-8. ISSN 0940-1334. PMID 12192466.
  4. ↑ Pallanti S, Quercioli L, Koran LM (September 2002). "Citalopram intravenous infusion in resistant obsessive-compulsive disorder: an open trial". The Journal of Clinical Psychiatry. 63 (9): 796–801. doi:10.4088/JCP.v63n0908. PMID 12363120.
  5. ↑ Altamura AC, Dell'Osso B, Buoli M, Zanoni S, Mundo E (August 2008). "Intravenous augmentative citalopram versus clomipramine in partial/nonresponder depressed patients: a short-term, low dose, randomized, placebo-controlled study". Journal of Clinical Psychopharmacology. 28 (4): 406–410. doi:10.1097/JCP.0b013e31817d5931. PMID 18626267. S2CID 25013120.
  6. ↑ Healy D, Bahrick A, Bak M, Barbato A, Calabro RS, Chubak BM (2022). "Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin". International Journal of Risk & Safety in Medicine. 33 (1): 65–76. doi:10.3233/JRS-210023. PMC 8925105. PMID 34719438.
  7. ↑ "PRAC recommendations on signals adopted at the 13-16 May 2019 PRAC meeting" (PDF). European Medicines Agency. 11 June 2019. Retrieved 8 April 2026.
  8. ↑ The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. 2023. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.
  9. ↑ British national formulary: BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 361. ISBN 978-0-85711-338-2.
  10. ↑ "Top 300 of 2023". ClinCalc. Archived from the original on 12 August 2025. Retrieved 12 August 2025.
  11. ↑ "Citalopram Drug Usage Statistics, United States, 2013 - 2023". ClinCalc. Archived from the original on 11 April 2020. Retrieved 18 August 2025.
  12. 1 2 3 4 5 6 7 "Pharmaceutical Benefits Scheme (PBS) - Citalopram". Australian Government Department of Health. Australian Government. Archived from the original on 11 September 2014. Retrieved 10 September 2014.
  13. ↑ "Depram". Apex (in American English). Retrieved 2024-12-23.
  14. ↑ El-beltagy M (5 July 2024). ديپرام: كل ما تريد معرفته عنه [Depram: all you need to know about it]. Teb Daily. Archived from the original on 19 January 2025. Retrieved 23 December 2024.
  15. ↑ "Lopraxer". International. Drugs.com. Archived from the original on 12 April 2020. Retrieved 12 April 2020.
  16. ↑ "Citalopram". International. Drugs.com. Archived from the original on 16 September 2018. Retrieved 23 January 2018.
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