Coeliac disease

celiac disease

class of disease, signs den symptoms

Subclass of	autoimmune disease of gastrointestinal tract, gluten-related disorder, disease
Age of onset	any age
Has cause	gluten
Health specialty	gastroenterology
Symptoms and signs	diarrhea, constipation, vomiting, nausea
Possible treatment	gluten-free diet
Described at URL	https://www.nhs.uk/conditions/coeliac-disease/, https://www.nice.org.uk/guidance/qs134, https://www.wikidoc.org/index.php/Celiac_disease
ICD-9-CM	579.0
ICPC 2 ID	D99
NCI Thesaurus ID	C26714

Coeliac disease (Commonwealth English) anaa celiac disease (American English) be a chronic autoimmune disease, mainly wey dey affect de small intestine, wey be caused by de consumption of gluten. Coeliac disease dey cause a wide range of symptoms den complications wey fi affect multiple organs outsyd of de gastrointestinal tract.

Symptoms fi be divided into two subtypes, classic den non-classic. De classic form of de disease fi affect any age group, buh be usually diagnosed insyd early childhood den dey cause symptoms of malabsorption such as weight loss, diarrhoea, den stunted growth. Non-classic coeliac disease be more commonly dem see insyd adults wey e be characterized by vague abdominal symptoms den complications insyd organs outsyd of de gastrointestinal tract, such as bone disease, anemia, den oda consequences of nutritional deficiencies.

Coeliac disease be caused by an abnormal immune system response to gluten, dem find insyd wheat den oda grains such as barley den rye. Wen an individual plus a genetic predisposition to de condition dey consume gluten, e dey trigger an inflammatory response insyd de small intestine, wey dey damage de intestinal lining, wey dey lead to malabsorption. Dem dey believe de development of coeliac disease to be influenced by oda environmental factors, such as infections.

Coeliac disease be diagnosed base on symptoms, blood tests, den biopsies of de small intestine while consuming a diet wey dey contain gluten. Insyd those wey already reduce dema gluten intake, reintroducing gluten fi be required to reach an accurate diagnosis. De diagnosis often be complicated by de diverse symptoms, overlap plus oda disorders, den lack of awareness, wey dey lead to a delay insyd diagnosis. Current research dey indicate say der no be enough evidence to advocate for mass screening for coeliac disease insyd those widout symptoms.

De treatment for coeliac disease per be a lifelong gluten-free diet (GFD). A GFD dey involve removing all chow den drink wich dey contain wheat, rye, barley den gluten derivatives. Symptoms fi improve within days of adopting a GFD den de diet dey improve quality of life, dey prevent further complications den dey normalize sam effects of de disease such as stunted growth.

Approximately 1 insyd 200 to 1 insyd 50 people get coeliac disease. Na diagnoses of coeliac disease increase in recently secof increased awareness den availability of blood testing. However, de disease still be thought to be underdiagnosed, plus a significant number of people plus de condition wey dey remain undiagnosed den untreated. Chaw people develop de disease before de age of 10 wey e be slightly more common insyd women dan insyd men.

Terminology den classification

"Coeliac disease" be de preferred spelling insyd Commonwealth English, while "celiac disease" be typically used insyd North American English.