Dracunculiasis
| Subclass of | nematode infection, parasitic helminthiasis infectious disease, filariasis, neglected tropical disease, disease |
|---|---|
| Ein location | human leg |
| Has cause | Dracunculus medinensis |
| Health specialty | infectious diseases, helminthology, tropical medicine |
| Drug or therapy used for treatment | thiabendazole |
| Disease transmission process | water pollution |
| ICD-9-CM | 125.7 |
Dracunculiasis, dem sanso call Guinea-worm disease, be a parasitic infection by de Guinea worm (Dracunculus medinensis). A person cam be infected by drinking water dem contaminate plus Guinea-worm larvae wey dey reside insyd copepods (a type of small crustacean). Stomach acid dey digest de copepod den dey release de Guinea worm larva, wich dey penetrate de digestive tract den dey escape into de body. Around a year later, de adult female worm dey migrate to an exit site – usually de lower leg – den dey induce an intensely painful blister on de skin. Eventually, de blister bursts, wey dey create a painful wound from wich de worm gradually dey emerge over several weeks. De wound remain painful thru out de worm ein emergence, wey dey disable de affected person for de three to ten weeks e dey take de worm to emerge. De female worm release larvae wen de host submerge de wound insyd water in attempts to relieve de pain, thus dey continue de life cycle.
Der be no medication to treat anaa prevent dracunculiasis. Instead, de mainstay of treatment be de careful wrapping of de emerging worm around a small stick anaa gauze to encourage den speed up ein exit. Each day, a few more centimeters of de worm emerge, den de stick be turned to maintain gentle tension. Too much tension fi break den kill de worm insyd de wound, wey dey cause severe pain den swelling. Dracunculiasis be a disease of extreme poverty, wey dey occur insyd places plus poor access to clean drinking water. Prevention efforts dey center on filtering drinking water to remove copepods as well as public education campaigns to discourage people from soaking affected limbs insyd sources of drinking water, as dis action dey allow de worms to spread dema larvae.
Accounts consistent plus dracunculiasis dey appear in surviving documents from physicians of Greco-Roman antiquity. Insyd de 19th den early 20th centuries, dracunculiasis be widespread across much of Africa den South Asia, wey dey affect as many as 48 million people per year. De effort to eradicate dracunculiasis begin insyd de 1980s dey follow de successful eradication of smallpox insyd 1977. By 1995, nearly every country plus endemic dracunculiasis establish a national eradication program. Insyd de ensuing years, dracunculiasis cases drop precipitously, wey dey fall below 100,000 cases per year insyd 1997, below 10,000 cases insyd 2007, below 1,000 cases insyd 2012, below 100 cases insyd 2015, den to 10 cases insyd 2025 per. Since 1986, 16 previously endemic countries eradicate dracunculiasis, wey dey leave de disease primarily endemic insyd three landlocked developing countries of central Africa – Chad, Ethiopia den South Sudan. Three additional countries remain to be certified as free of dracunculiasis transmission wey dem get no reported human cases since de end of 2023: Angola, Mali, den Sudan. One of dese, Sudan, be pre-certified buh no yet be confirmed free of transmissions. Additionally, although na Cameroon be certified free of internal transmission since 2007, e experience three cases since 2019 along ein border plus Chad. D. medinensis sanso fi infect dogs, cats, den baboons, though non-human cases sanso dey fall secof de eradication efforts. Oda Dracunculus species dey cause dracunculiasis insyd reptiles worldwide den insyd mammals insyd de Americas.
Insyd 2020, de World Health Organization set 2027 as ein target date for eradication of dracunculiasis. If de eradication program succeed, dracunculiasis be expected to cam be tde second human disease to be eradicated, after smallpox.
References
[edit | edit source]- Biswas G, Sankara DP, Agua-Agum J, Maiga A (August 2013). "Dracunculiasis (Guinea worm disease): eradication without a drug or a vaccine". Philosophical Transactions of the Royal Society B. 368 (1623) 20120146. doi:10.1098/rstb.2012.0146. PMC 3720044. PMID 23798694.
- Callahan K, Bolton B, Hopkins DR, Ruiz-Tiben E, Withers PC, Meagley K (30 May 2013). "Contributions of the Guinea Worm Disease eradication campaign toward achievement of the Millennium Development Goals". PLOS Neglected Tropical Diseases. 7 (5) e2160. doi:10.1371/journal.pntd.0002160. PMC 3667764. PMID 23738022.
- Cleveland CA, Garrett KB, Cozad RA, Williams BM, Murray MH, Yabsley MJ (December 2018). "The wild world of Guinea Worms: A review of the genus Dracunculus in wildlife". International Journal for Parasitology: Parasites and Wildlife. 7 (3): 289–300. Bibcode:2018IJPPW...7..289C. doi:10.1016/j.ijppaw.2018.07.002. PMC 6072916. PMID 30094178.
- Despommier DD, Griffin DO, Gwadz RW, Hotez PJ, Knirsch CA (2019). "25. Dracunculus medinensis". Parasitic Diseases (PDF) (7 ed.). Parasites Without Borders. pp. 285–290. Archived (PDF) from the original on 24 November 2021. Retrieved 26 January 2021.
- Eberhard ML, Ruiz-Tiben E, Hopkins DR, Farrell C, Toe F, Weiss A, Withers PC, Jenks MH, Thiele EA, Cotton JA, Hance Z, Holroyd N, Cama VA, Tahir MA, Mounda T (January 2014). "The peculiar epidemiology of dracunculiasis in Chad". American Journal of Tropical Medicine and Hygiene. 90 (1): 61–70. doi:10.4269/ajtmh.13-0554. PMC 3886430. PMID 24277785.
- Greenaway C (February 2004). "Dracunculiasis (Guinea worm disease)". Canadian Medical Association Journal. 170 (4): 495–500. PMC 332717. PMID 14970098.
- Grove DI (1990). A History of Human Helminthology (PDF). C.A.B International. Archived (PDF) from the original on 4 April 2015. Retrieved 13 March 2022.
- Hopkins DR, Ruiz-Tiben E, Eberhard ML, Weiss A, Withers PC, Roy SL, Sienko DG (August 2018). "Dracunculiasis eradication: are we there yet?". American Journal of Tropical Medicine and Hygiene. 99 (2): 388–395. doi:10.4269/ajtmh.18-0204. PMC 6090361. PMID 29869608.
- Hopkins DR, Weiss AJ, Roy SL, Yerian S, Cama VA (November 2021). "Progress toward global eradication of dracunculiasis, January 2020–June 2021". Morbidity and Mortality Weekly Report. 70 (44): 1527–1533. doi:10.15585/mmwr.mm7044a1. PMC 8568094. PMID 34735420.
- Hopkins DR, Weiss AJ, Torres-Velez FJ, Sapp SG, Ijaz K (August 2022). "Dracunculiasis eradication: end-stage challenges". American Journal of Tropical Medicine and Hygiene. 107 (2): 373–382. doi:10.4269/ajtmh.22-0197. PMC 9393450. PMID 35895421.
- Hotez PJ (2013). "The filarial infections: lymphatic filariasis (elephantiasis) and dracunculiasis (Guinea worm)". Forgotten People, Forgotten Diseases: The Neglected Tropical Diseases and Their Impact on Global Health and Development. American Society for Microbiology (ASM) Press. pp. 57–75. doi:10.1128/9781555818753.ch4. ISBN 978-1-55581-874-6.
- Miller RL (1989). "Dqr, spinning and treatment of Guinea worm in P. Ebers 875". The Journal of Egyptian Archaeology. 75: 249–254. doi:10.2307/3821922. JSTOR 3821922.
- Molyneux D, Sankara DP (April 2017). "Guinea worm eradication: Progress and challenges— should we beware of the dog?". PLOS Neglected Tropical Diseases. 11 (4) e0005495. doi:10.1371/journal.pntd.0005495. PMC 5398503. PMID 28426663.
- Ruiz-Tiben E, Hopkins DR (2006). "Dracunculiasis (Guinea worm disease) eradication". Advances in Parasitology. 61: 275–309. doi:10.1016/S0065-308X(05)61007-X. ISBN 978-0-12-031761-5. PMID 16735167.
- Spector JM, Gibson TE, eds. (2016). "Dracunculiasis". Atlas of Pediatrics in the Tropics and Resource-Limited Settings (2 ed.). American Academy of Pediatrics. pp. 109–115. ISBN 978-1-58110-960-3.
- Dracunculiasis eradication: global surveillance summary, 2021 (Report). World Health Organization. 27 May 2022. Archived from the original on 29 July 2022. Retrieved 29 July 2022.
External links
[edit | edit source]- Dracunculiasis (Guinea-worm disease) fact sheet published by the World Health Organization
- Guinea Worm Disease Eradication Program—Carter Center
- Anyak vs. the Guinea Worm—Nicholas D. Kristof from The New York Times follows a young Sudanese boy with a Guinea worm parasite infection who is quarantined for treatment as part of the Carter Center program