Jump to content

Epinephrine

From Wikipedia
epinephrine
type of chemical entity
Subclass of(±)-adrenaline Edit
Get useMedication Edit
Stylized nameEPINEPHrine Edit
Stereoisomer of(S)-racepinefrine Edit
Chemical formulaC₉H₁₃NO₃ Edit
Canonical SMILESCNCC(C1=CC(=C(C=C1)O)O)O Edit
Isomeric SMILESCNC[C@@H](C1=CC(=C(C=C1)O)O)O Edit
Active ingredient inAuvi-Q, Epinephrine autoinjector, Adrenalin, Symjepi Edit
World Health Organisation international non-proprietary nameepinephrine Edit
Pregnancy categoryUS pregnancy category C Edit
Subject has rolealpha-adrenergic agonist, Adrenergic beta-2 Agonists, adrenergic beta-agonists, neurotransmitter, stress hormone Edit
WordLift URLhttp://data.wordlift.io/wl01714/entity/epinephrine.html Edit

Adrenaline, dem sanso know as epinephrine den alternatively dem spell adrenalin, be a hormone den medication[1][2] wich be involved insyd regulating visceral functions (e.g., respiration).[1][3] E dey appear as a white microcrystalline granule.[4] Adrenaline be normally produced by de adrenal glands den by a small number of neurons insyd de medulla oblongata.[5] E dey play an essential role insyd de fight-or-flight response by increasing blood flow to muscles, heart output by acting on de SA node,[6] pupil dilation response, den blood sugar level.[7][8] E dey do dis by binding to alpha den beta receptors.[8] E be found insyd chaw animals, wey dey include humans, den sam single-celled organisms.[9][10] E sanso be isolated from de plant Scoparia dulcis dem find insyd Northern Vietnam.[11]

References

[edit | edit source]
  1. 1 2 Lieberman M, Marks A, Peet A (2013). Marks' Basic Medical Biochemistry: A Clinical Approach (4th ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 175. ISBN 978-1-60831-572-7.
  2. "Adrenaline". 21 August 2015.
  3. Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 6: Widely Projecting Systems: Monoamines, Acetylcholine, and Orexin". In Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York, USA: McGraw-Hill Medical. p. 157. ISBN 978-0-07-148127-4. Epinephrine occurs in only a small number of central neurons, all located in the medulla. Epinephrine is involved in visceral functions, such as the control of respiration. It is also produced by the adrenal medulla.
  4. Larrañaga M (2016). Hawley's Condensed Chemical Dictionary. New Jersey: John Wiley & Sons, Incorporated. p. 561.
  5. "Adrenaline: physiology and pharmacology | DermNet". dermnetnz.org. Retrieved 2023-03-20.
  6. Brown HF, DiFrancesco D, Noble SJ (July 1979). "How does adrenaline accelerate the heart?". Nature. 280 (5719): 235–236. Bibcode:1979Natur.280..235B. doi:10.1038/280235a0. PMID 450140. S2CID 4350616.
  7. Bell DR (2009). Medical physiology: principles for clinical medicine (3rd ed.). Philadelphia: Lippincott Williams & Wilkins. p. 312. ISBN 978-0-7817-6852-8.
  8. 1 2 Khurana I (2008). Essentials of Medical Physiology. Elsevier India. p. 460. ISBN 978-81-312-1566-1.
  9. Buckley E (2013). Venomous Animals and Their Venoms: Venomous Vertebrates. Elsevier. p. 478. ISBN 978-1-4832-6288-8.
  10. Animal Physiology: Adaptation and Environment (5th ed.). Cambridge University Press. 1997. p. 510. ISBN 978-1-107-26850-0.
  11. Phan MG, Phan TS, Matsunami K, Otsuka H (April 2006). "Chemical and biological evaluation on scopadulane-type diterpenoids from Scoparia dulcis of Vietnamese origin". Chemical & Pharmaceutical Bulletin. 54 (4): 546–549. doi:10.1248/cpb.54.546. PMID 16595962.
[edit | edit source]