Epinephrine
| Subclass of | (±)-adrenaline |
|---|---|
| Get use | Medication |
| Stylized name | EPINEPHrine |
| Stereoisomer of | (S)-racepinefrine |
| Chemical formula | C₉H₁₃NO₃ |
| Canonical SMILES | CNCC(C1=CC(=C(C=C1)O)O)O |
| Isomeric SMILES | CNC[C@@H](C1=CC(=C(C=C1)O)O)O |
| Active ingredient in | Auvi-Q, Epinephrine autoinjector, Adrenalin, Symjepi |
| World Health Organisation international non-proprietary name | epinephrine |
| Pregnancy category | US pregnancy category C |
| Subject has role | alpha-adrenergic agonist, Adrenergic beta-2 Agonists, adrenergic beta-agonists, neurotransmitter, stress hormone |
| WordLift URL | http://data.wordlift.io/wl01714/entity/epinephrine.html |
Adrenaline, dem sanso know as epinephrine den alternatively dem spell adrenalin, be a hormone den medication[1][2] wich be involved insyd regulating visceral functions (e.g., respiration).[1][3] E dey appear as a white microcrystalline granule.[4] Adrenaline be normally produced by de adrenal glands den by a small number of neurons insyd de medulla oblongata.[5] E dey play an essential role insyd de fight-or-flight response by increasing blood flow to muscles, heart output by acting on de SA node,[6] pupil dilation response, den blood sugar level.[7][8] E dey do dis by binding to alpha den beta receptors.[8] E be found insyd chaw animals, wey dey include humans, den sam single-celled organisms.[9][10] E sanso be isolated from de plant Scoparia dulcis dem find insyd Northern Vietnam.[11]
References
[edit | edit source]- 1 2 Lieberman M, Marks A, Peet A (2013). Marks' Basic Medical Biochemistry: A Clinical Approach (4th ed.). Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 175. ISBN 978-1-60831-572-7.
- ↑ "Adrenaline". 21 August 2015.
- ↑ Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 6: Widely Projecting Systems: Monoamines, Acetylcholine, and Orexin". In Sydor A, Brown RY (eds.). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd ed.). New York, USA: McGraw-Hill Medical. p. 157. ISBN 978-0-07-148127-4.
Epinephrine occurs in only a small number of central neurons, all located in the medulla. Epinephrine is involved in visceral functions, such as the control of respiration. It is also produced by the adrenal medulla.
- ↑ Larrañaga M (2016). Hawley's Condensed Chemical Dictionary. New Jersey: John Wiley & Sons, Incorporated. p. 561.
- ↑ "Adrenaline: physiology and pharmacology | DermNet". dermnetnz.org. Retrieved 2023-03-20.
- ↑ Brown HF, DiFrancesco D, Noble SJ (July 1979). "How does adrenaline accelerate the heart?". Nature. 280 (5719): 235–236. Bibcode:1979Natur.280..235B. doi:10.1038/280235a0. PMID 450140. S2CID 4350616.
- ↑ Bell DR (2009). Medical physiology: principles for clinical medicine (3rd ed.). Philadelphia: Lippincott Williams & Wilkins. p. 312. ISBN 978-0-7817-6852-8.
- 1 2 Khurana I (2008). Essentials of Medical Physiology. Elsevier India. p. 460. ISBN 978-81-312-1566-1.
- ↑ Buckley E (2013). Venomous Animals and Their Venoms: Venomous Vertebrates. Elsevier. p. 478. ISBN 978-1-4832-6288-8.
- ↑ Animal Physiology: Adaptation and Environment (5th ed.). Cambridge University Press. 1997. p. 510. ISBN 978-1-107-26850-0.
- ↑ Phan MG, Phan TS, Matsunami K, Otsuka H (April 2006). "Chemical and biological evaluation on scopadulane-type diterpenoids from Scoparia dulcis of Vietnamese origin". Chemical & Pharmaceutical Bulletin. 54 (4): 546–549. doi:10.1248/cpb.54.546. PMID 16595962.
External links
[edit | edit source]- "U.S. National Library of Medicine: Drug Information Portal – Epinephrine". Archived from the original on 14 December 2019.
- Pages using Sister project links with hidden wikidata
- Adrenaline
- Anxiety
- Articles wey dey contain video clips
- Alpha-adrenergic agonists
- Beta-adrenergic agonists
- Bronchodilators
- Carbonic anhydrase activators
- Cardiac stimulants
- Catecholamines
- Hormones of de hypothalamus-pituitary-adrenal axis
- Hormones of de suprarenal medulla
- Norepinephrine releasing agents
- Stress (biology)
- Sympathomimetic amines
- Chemical substances for emergency medicine
- Phenylethanolamines
- Human metabolites
- Stress hormones
- Over-the-counter drugs insyd de United States
- Translated from MDWiki