Fatal insomnia
fatal familial insomnia
| Subclass of | inherited prion disease, thalamic disease, insomnia  |
|---|---|
| Short name | FFI |
| Health specialty | psychiatry, sleep medicine, neuropathology |
| Genetic association | PRNP |
| ICD-9-CM | 046.72 |
| ICPC 2 ID | N73 |
Fatal insomnia be a neurodegenerative disease wey dey result in trouble sleeping as ein hallmark symptom.[1] De majority of cases be familial (fatal familial insomnia [FFI]), wey dey stem from a mutation insyd de PRNP gene, plus de remainder of cases wey dey occur sporadically (sporadic fatal insomnia [sFI]). De problems plus sleeping typically dey start out gradually den worsen over time.[2] Eventually, de patient go succumb to total insomnia (agrypnia excitata), most often wey dey lead to oda symptoms such as speech problems, coordination problems, den dementia.[3] E dey result in death within a few months to a few years, wey der no be known disease-modifying treatment.[1]
References
[edit | edit source]- 1 2 "Fatal Insomnia - Neurologic Disorders". Merck Manual Professional Edition (in Canadian English). Retrieved 2026-01-15.
- ↑ "Fatal Familial Insomnia Symptoms, Causes, Treatment | NORD" (in American English). Retrieved 2026-01-15.
- ↑ "Fatal Insomnia". Merck Manual. Retrieved 4 May 2018.
External links
[edit | edit source]
Wikimedia Commons get media wey relate to Fatal insomnia.
- "AFIFF Fatal Familial Insomnia Families Association". Archived from the original on 21 October 2016. Retrieved 26 January 2013.
| Authority control databases: National |
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Categories:
- CS1 Canadian English-language sources (en-ca)
- CS1 American English-language sources (en-us)
- Commons category link from Wikidata
- Neurodegenerative disorders
- Transmissible spongiform encephalopathies
- Unsolved problems insyd neuroscience
- Sleep disorders
- Rare diseases
- Sleeplessness den sleep deprivation
- Translated from MDWiki