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Giardiasis

From Wikipedia
giardiasis
infectious disease, class of disease
Subclass ofparasitic protozoa infectious disease, waterborne disease, disease Edit
Dem name afterAlfred Mathieu Giard Edit
Has causeGiardia lamblia Edit
Health specialtyinfectious diseases, gastroenterology Edit
Medical examinationoptical microscope, ELISA, immunofluorescence microscopy Edit
Disease transmission processfecal–oral route Edit
Has natural reservoirhuman Edit
ICD-9-CM007.1 Edit

Giardiasis be a parasitic disease wey de protist enteropathogen Giardia duodenalis (dem sanso know as G. lamblia den G. intestinalis) cause, especially common insyd kiddies den travelers.[1][2] Infected individuals dey experience steatorrhea, a type of diarrhea plus fatty sticky stool; abdominal pain, weight loss, den weakness secof dehydration den malabsorption.[3] Less common symptoms dey include skin rash, hives den joint swelling.[3] Symptoms usually dey begin one to three weeks after exposure den, widout treatment, fi last two to six weeks anaa longer.[4] Sam infected individuals dey experience mild anaa no symptoms den remain symptom-free even if de infection persist for a long time.[5]

Giardiasis dey spread via de fecal-oral route, wen Giardia cysts excrete plus feces contaminate chow anaa water wey later be consumed orally.[3] De disease sanso fi spread between people den between people den animals, mainly via pets.[3][6][7] Cysts fi survive for nearly three months insyd cold water.[3]

De microscopic identification of Giardia den ein cysts insyd fecal samples be considered de gold standard method for diagnosing giardiasis.[8] Immunoassays, such as ELISA den PCR for giardia gene loci, sanso be available as diagnostic tools, although no be widely used secof methods complexity den costs.[8]

Prevention fi be improved thru proper personal hygiene practices den by cooking den sanitizing chow.[3] Asymptomatic cases often no dey hia treatment. Wen symptoms be present, treatment typically be provided plus either tinidazole anaa metronidazole.[3] Oda drugs, such as nitazoxanide, albendazole, quinacrine, chloroquine, paromomycin, den oda drug combinations sanso be used insyd clinics.[9] Refractory giardiasis den resistant strains be reported more den more often.[10] Infection fi cause a person make e cam be lactose intolerant, so e be recommended to temporarily avoid lactose dey follow an infection anaa use lactase supplements.[3]

Giardiasis dey occur worldwide.[11] E be one of de most common parasitic human diseases.[1] Infection rates be as high as 7% insyd de developed world den 30% insyd de developing world.[3] Insyd 2013, der be approximately 280 million people worldwide plus symptomatic cases of giardiasis.[1] De World Health Organization dey classify giardiasis as a neglected disease.[3] E be popularly known as beaver fever[12] insyd North America.

References

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  1. 1 2 3 Esch KJ, Petersen CA (January 2013). "Transmission and epidemiology of zoonotic protozoal diseases of companion animals". Clinical Microbiology Reviews. 26 (1): 58–85. doi:10.1128/CMR.00067-12. PMC 3553666. PMID 23297259.
  2. Buret, A.G. (September 2008). "Pathophysiology of enteric infections with Giardia duodenalis". Parasite. 15 (3): 261–265. doi:10.1051/parasite/2008153261. ISSN 1252-607X. PMID 18814692.
  3. 1 2 3 4 5 6 7 8 9 10 Minetti C, Chalmers RM, Beeching NJ, Probert C, Lamden K (October 2016). "Giardiasis" (PDF). BMJ. 355 i5369. doi:10.1136/bmj.i5369. PMID 27789441. S2CID 220092781. Archived from the original (PDF) on 2019-11-06. Retrieved 2019-11-06.
  4. "Giardia. Illness and symptoms". CDC. 26 February 2021. Retrieved 27 March 2022.
  5. "Giardiasis fact sheet". www.health.nsw.gov.au (in English). Retrieved 2025-06-03.
  6. Heyworth MF (2016). "Giardia duodenalis genetic assemblages and hosts". Parasite. 23: 13. doi:10.1051/parasite/2016013. PMC 4794627. PMID 26984116. Archived from the original on 2017-09-10.
  7. Cacciò, Simone M.; Lalle, Marco; Svärd, Staffan G. (December 2018). "Host specificity in the Giardia duodenalis species complex". Infection, Genetics and Evolution (in English). 66: 335–345. Bibcode:2018InfGE..66..335C. doi:10.1016/j.meegid.2017.12.001. PMID 29225147.
  8. 1 2 Vicente, Bruno; Freitas, Anna De; Freitas, Marcus; Midlej, Victor (2024-02-07). "Systematic Review of Diagnostic Approaches for Human Giardiasis: Unveiling Optimal Strategies". Diagnostics (in English). 14 (4): 364. doi:10.3390/diagnostics14040364. ISSN 2075-4418. PMC 10887752. PMID 38396402.
  9. Lalle, Marco; Hanevik, Kurt (2018-10-24). "Treatment-refractory giardiasis: challenges and solutions". Infection and Drug Resistance (in English). 11: 1921–1933. doi:10.2147/IDR.S141468. PMC 6207226. PMID 30498364.
  10. Nabarro, L. E. B.; Lever, R. A.; Armstrong, M.; Chiodini, P. L. (2015-08-01). "Increased incidence of nitroimidazole-refractory giardiasis at the Hospital for Tropical Diseases, London: 2008–2013". Clinical Microbiology and Infection (in English). 21 (8): 791–796. doi:10.1016/j.cmi.2015.04.019. ISSN 1198-743X. PMID 25975511.
  11. "Giardiasis". cdc.gov. December 9, 2017. Archived from the original on April 14, 2021. Retrieved 27 March 2022.
  12. "Giardiasis (beaver fever)". New York State Department of Health. January 2022. Archived from the original on 20 January 2022. Retrieved 27 March 2022.
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