Hantavirus infection
Hantavirus infection anaa hantavirus disease be an infectious disease of humans wey viruses insyd de Orthohantavirus genus of viruses cause. E fi result in hemorrhagic fever plus renal syndrome (HFRS) anaa hantavirus pulmonary syndrome (HPS).[1] Symptoms of HFRS generally dey include headache, abdominal pain, fever, nausea, bleeding, den kidney failure.[2] Symptoms of HPS dey include tiredness, fever, muscle pain, cough, den shortness of breath.[3] Onset of initial symptoms generally be 1 to 8 weeks dey follow exposure.[2][3]
HFRS be secof Old World hantaviruses while HPS be secof New World hantaviruses.[1] More dan 28 specific hantaviruses dey cause disease insyd humans.[4] De disease typically be spread wen people breathe in air wey be contaminated by rodent droppings.[4] De underlying mechanism of both forms of de disease dey involve low platelets den leaky blood vessels.[4] Diagnosis be based on blood tests, typically serology.[4]
Treatment primarily be supportive care.[5] Dis fi include oxygen therapy, mechanical ventilation, dialysis, anaa platelet transfusions.[5] Ribavirin fi be useful if dem give am early insyd HFRS.[5] De risk of death be around 12% plus HFRS den around 40% plus HPS.[5]
About 100,000 cases of HFRS dey occur a year, while about 1,000 cases of HPS be identified since dem first detect am insyd 1993.[5] While descriptions of wat be believed to be hantavirus infections dey date back to around 1000 AD,[5] de virus wey dey cause de disease dem no discover am til 1976, insyd de Hantan River area of South Korea.[5][6]
Insyd April 2026, an outbreak of hantavirus infection wey de Andes virus cause dem identify am on de Dutch cruise ship MV Hondius.[7]
Diagnosis
[edit | edit source]In terms of de evaluation of dis infection dem dey do de following:[8]
- Chest X-ray (pulmonary edema)
- Blood workup (thrombocytopenia)
- Immunofluorescent anaa immunoblot assay (ELISA utilizing IgM)
References
[edit | edit source]- 1 2 "CDC - Hantavirus". www.cdc.gov (in American English). 9 September 2020. Archived from the original on 28 January 2007. Retrieved 25 March 2021.
- 1 2 "CDC - Hemorrhagic Fever with Renal Syndrome (HFRS) - Hantavirus". www.cdc.gov (in American English). 22 February 2019. Archived from the original on 16 November 2019. Retrieved 29 March 2021.
- 1 2 "Signs & Symptoms | Hantavirus | DHCPP | CDC". www.cdc.gov (in American English). 22 February 2019. Archived from the original on 20 March 2021. Retrieved 28 March 2021.
- 1 2 3 4 Avšič-Županc T, Saksida A, Korva M (2019). "Hantavirus infections". Clin Microbiol Infect. 21S: e6 – e16. doi:10.1111/1469-0691.12291. PMID 24750436.
- 1 2 3 4 5 6 7 Avšič-Županc T, Saksida A, Korva M (2019). "Hantavirus infections". Clin Microbiol Infect. 21S: e6 – e16. doi:10.1111/1469-0691.12291. PMID 24750436.
- ↑ "ICTV 9th Report (2011) – Negative Sense RNA Viruses – Bunyaviridae". International Committee on Taxonomy of Viruses (ICTV) (in English). Archived from the original on 11 December 2018. Retrieved 31 January 2019.
Hanta: from Hantaan, river in South Korea near where type virus was isolated.
- ↑ "A suspected outbreak of the rare hantavirus on a cruise ship in the Atlantic kills 3 people". AP News. 3 May 2026. Retrieved 4 May 2026.
- ↑ Moore, Ross A.; Griffen, David (2021). "Hantavirus Syndrome". StatPearls. StatPearls Publishing. PMID 30020615. Archived from the original on 20 March 2021. Retrieved 27 November 2021.