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Hantavirus infection

From Wikipedia
Hantavirus infectious disease
Subclass ofBunyaviridae infectious disease Edit
Has causeinfection Edit

Hantavirus infection anaa hantavirus disease be an infectious disease of humans wey viruses insyd de Orthohantavirus genus of viruses cause. E fi result in hemorrhagic fever plus renal syndrome (HFRS) anaa hantavirus pulmonary syndrome (HPS).[1] Symptoms of HFRS generally dey include headache, abdominal pain, fever, nausea, bleeding, den kidney failure.[2] Symptoms of HPS dey include tiredness, fever, muscle pain, cough, den shortness of breath.[3] Onset of initial symptoms generally be 1 to 8 weeks dey follow exposure.[2][3]

HFRS be secof Old World hantaviruses while HPS be secof New World hantaviruses.[1] More dan 28 specific hantaviruses dey cause disease insyd humans.[4] De disease typically be spread wen people breathe in air wey be contaminated by rodent droppings.[4] De underlying mechanism of both forms of de disease dey involve low platelets den leaky blood vessels.[4] Diagnosis be based on blood tests, typically serology.[4]

Treatment primarily be supportive care.[5] Dis fi include oxygen therapy, mechanical ventilation, dialysis, anaa platelet transfusions.[5] Ribavirin fi be useful if dem give am early insyd HFRS.[5] De risk of death be around 12% plus HFRS den around 40% plus HPS.[5]

About 100,000 cases of HFRS dey occur a year, while about 1,000 cases of HPS be identified since dem first detect am insyd 1993.[5] While descriptions of wat be believed to be hantavirus infections dey date back to around 1000 AD,[5] de virus wey dey cause de disease dem no discover am til 1976, insyd de Hantan River area of South Korea.[5][6]

Insyd April 2026, an outbreak of hantavirus infection wey de Andes virus cause dem identify am on de Dutch cruise ship MV Hondius.[7]

Diagnosis

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In terms of de evaluation of dis infection dem dey do de following:[8]

  • Chest X-ray (pulmonary edema)
  • Blood workup (thrombocytopenia)
  • Immunofluorescent anaa immunoblot assay (ELISA utilizing IgM)

References

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  1. 1 2 "CDC - Hantavirus". www.cdc.gov (in American English). 9 September 2020. Archived from the original on 28 January 2007. Retrieved 25 March 2021.
  2. 1 2 "CDC - Hemorrhagic Fever with Renal Syndrome (HFRS) - Hantavirus". www.cdc.gov (in American English). 22 February 2019. Archived from the original on 16 November 2019. Retrieved 29 March 2021.
  3. 1 2 "Signs & Symptoms | Hantavirus | DHCPP | CDC". www.cdc.gov (in American English). 22 February 2019. Archived from the original on 20 March 2021. Retrieved 28 March 2021.
  4. 1 2 3 4 Avšič-Županc T, Saksida A, Korva M (2019). "Hantavirus infections". Clin Microbiol Infect. 21S: e6 – e16. doi:10.1111/1469-0691.12291. PMID 24750436.
  5. 1 2 3 4 5 6 7 Avšič-Županc T, Saksida A, Korva M (2019). "Hantavirus infections". Clin Microbiol Infect. 21S: e6 – e16. doi:10.1111/1469-0691.12291. PMID 24750436.
  6. "ICTV 9th Report (2011) – Negative Sense RNA Viruses – Bunyaviridae". International Committee on Taxonomy of Viruses (ICTV) (in English). Archived from the original on 11 December 2018. Retrieved 31 January 2019. Hanta: from Hantaan, river in South Korea near where type virus was isolated.
  7. "A suspected outbreak of the rare hantavirus on a cruise ship in the Atlantic kills 3 people". AP News. 3 May 2026. Retrieved 4 May 2026.
  8. Moore, Ross A.; Griffen, David (2021). "Hantavirus Syndrome". StatPearls. StatPearls Publishing. PMID 30020615. Archived from the original on 20 March 2021. Retrieved 27 November 2021.
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