Kallmann syndrome

Kallmann syndrome

class of disease

Subclass of	hypogonadotropic hypogonadism, disease, intersex variation
Dem name after	Franz Josef Kallmann
Health specialty	endocrinology
Symptoms and signs	anosmia, hypogonadism, osteoporosis, infertility
NCI Thesaurus ID	C75479

Kallmann syndrome (KS) be a genetic disorder wey dey prevent a person from starting anaa fully completing puberty. Kallmann syndrome be one of a group of conditions dem term hypogonadotropic hypogonadism. To distinguish am from oda forms of hypogonadotropic hypogonadism, Kallmann syndrome get de additional symptom of a total lack of sense of smell (anosmia) anaa a reduced sense of smell. If dem lef am untreated, people go get poorly defined secondary sexual characteristics, dey show signs of hypogonadism, almost invariably be infertile den at increased risk of dem dey develop osteoporosis. A range of oda physical symptoms wey dey affect de face, hands den skeletal system sanso fi occur.

Terminology

De terminology dem dey use wen describing cases of HH vary den fi include:

• GnRH deficiency
• congenital hypogonadotropic hypogonadism (CHH)
• idiopathic/isolated hypogonadotropic hypogonadism (IHH)
• normosmic hypogonadotropic hypogonadism (nHH)
• hypothalamic hypogonadism
• olfacto-genital syndrome

External links

• National Organization for Rare Diseases page on Kallmann syndrome