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Leprosy

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Leprosy
Other namesHansen disease (HD)[1]
Rash on de chest den abdomen secof leprosy
SpecialtyInfectious disease
SymptomsDecreased ability to feel pain
CausesMycobacterium leprae anaa Mycobacterium lepromatosis[2]
Risk factorsClose contact plus a case of leprosy, living insyd poverty[3]
TreatmentMultidrug therapy
MedicationRifampicin, dapsone, clofazimine
Frequency127,558 (2020)

Leprosy, dem sanso know am as Hansen's disease (HD), be a long-term infection by de bacteria Mycobacterium leprae anaa Mycobacterium lepromatosis.[4][5] Infection fi lead to damage of de nerves, respiratory tract, skin, den eyes.[4] Dis nerve damage fi result insyd a lack of ability to feel pain, wich fi lead to de loss of parts of a person ein extremities from repeated injuries anaa infection thru unnoticed wounds.[6] An infected person sanso fi experience muscle weakness den poor eyesight.[6] Leprosy symptoms fi begin within one year, buh for sam people symptoms fi take 20 years anaa more make e occur.[4]

Notable cases

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Father Damien for ein deathbed top for 14 April 1889
  • Josephine Cafrine of Seychelles (1877–1907) na she get leprosy from age 12 wey na she keep a journal wey document ein struggles den suffering.[7][8][9] Na she publish as an autobiography insyd 1923.[7][8][9][10]
  • Saint Damien De Veuster (1840–1889), a Catholic priest wey komot Belgium, contract leprosy wey he minister to lepers.[11]
  • Baldwin IV of Jerusalem (1161–1185), Catholic king of Latin Jerusalem, na he get leprosy.[12]
  • Ingeborg Grytten (c. 1668 – after 1705), Norwegian writer.[13]
  • Josefina Guerrero (1917–1996), Filipino World War II spy.[14]
  • King Henry IV of England (r. 1399–1413) possibly get leprosy.[15]
  • Vietnamese poet Hàn Mặc Tử (1912–1940)[16]
  • Ōtani Yoshitsugu (1558 anaa 1565–1600), a Japanese daimyō (feudal lord).[17]
  • British writer Peter Greave (1910–1977).
  • Popular Indian actress Dimple Kapadia (1957–present) na dem diagnose am plus leprosy a few months before de shoot of de 1973 musical romance film, Bobby (1973 film). Na she later recover completely wey na she go on go get a successful acting career.[18]

Insyd media

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  • August 1891 — de short story collection Life's Handicap by Rudyard Kipling get a story "The Mark of the Beast" insyd wich a traveller for horseback literally stumble into a leper colony insyd India.[19]
  • 1909 — na Jack London publish "Koolau the Leper" insyd ein Tales of Hawai'i about Molokai den people consign to am circa 1893.
  • 1959 — James Michener ein novel Hawaii dey dramatize Molokai ein leper settlement, wey dey include Father Damien.
  • 1959 — Ben-Hur dey depict de title character ein mommie, Miriam, den younger sisto, Tirzah, na de Roman Empire imprison dem. Wen na dem free dem years later, dem get leprosy wey dem lef town for de Valley of de Lepers, rada dan make dem stay den reunite plus Ben-Hur. Dem lef de colony, den wen Jesus die for de cross top, na dem be cured miraculously.
  • 1960 — English author Graham Greene ein novel A Burnt-Out Case be set insyd a leper colony insyd Belgian Congo. De story sanso be predominantly about a disillusioned architect wey dey work plus a doctor on devising new cures den amenities give mutilated victims of lepers; de title, too, dey refer to de condition of mutilation den disfigurement insyd de disease.[20]
  • 1962 — na Forugh Farrokhzad make a 22-minute documentary about a leprosy colony insyd Iran dem title The House Is Black.
  • 1977 — De lead character insyd The Chronicles of Thomas Covenant by Stephen R. Donaldson dey suffer from leprosy.
  • 2006 — Moloka'i be a novel by Alan Brennert about a leper colony insyd Hawaii.
  • 2009 — Squint: My Journey with Leprosy be a memoir by Jose P. Ramirez.[21]

References

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  1. ↑ Worobec, SM (2008). "Treatment of leprosy/Hansen's disease in the early 21st century". Dermatologic Therapy. 22 (6): 518–37. doi:10.1111/j.1529-8019.2009.01274.x. PMID 19889136.
  2. ↑ "New Leprosy Bacterium: Scientists Use Genetic Fingerprint To Nail 'Killing Organism'". ScienceDaily. 2008-11-28. Archived from the original on 2010-03-13. Retrieved 2010-01-31.
  3. ↑ Schreuder, P.A.M.; Noto, S.; Richardus J.H. (January 2016). "Epidemiologic trends of leprosy for the 21st century". Clinics in Dermatology. 34 (1): 24–31. doi:10.1016/j.clindermatol.2015.11.001. PMID 26773620.
  4. ↑ 4.0 4.1 4.2 "Leprosy". World Health Organization (WHO). Archived from the original on 31 January 2021. Retrieved 10 February 2020.
  5. ↑ Sotiriou MC, Stryjewska BM, Hill C (September 2016). "Two Cases of Leprosy in Siblings Caused by Mycobacterium lepromatosis and Review of the Literature". The American Journal of Tropical Medicine and Hygiene. 95 (3): 522–527. doi:10.4269/ajtmh.16-0076. PMC 5014252. PMID 27402522.
  6. ↑ 6.0 6.1 Suzuki K, Akama T, Kawashima A, Yoshihara A, Yotsu RR, Ishii N (February 2012). "Current status of leprosy: epidemiology, basic science and clinical perspectives". The Journal of Dermatology. 39 (2): 121–129. doi:10.1111/j.1346-8138.2011.01370.x. PMID 21973237. S2CID 40027505.
  7. ↑ 7.0 7.1 "A look at 6 contested historical events of Seychelles". Seychelles News Agency. Archived from the original on 17 November 2017. Retrieved 15 November 2017.
  8. ↑ 8.0 8.1 "Seychelles: 14 Inspiring Women of Seychelles". Seychelles News Agency (Victoria). 9 March 2017. Archived from the original on 17 November 2017. Retrieved 15 November 2017.
  9. ↑ 9.0 9.1 "Nation Home". Seychelles Nation. 14 January 2016. Archived from the original on 17 November 2017. Retrieved 16 November 2017.
  10. ↑ "Diocesan committee prepares to commemorate Josephine Cafrine's 109th death anniversary". Seychelles Weekly. 8 January 2016. Archived from the original on 4 April 2016. Retrieved 15 November 2017.
  11. ↑ Tayman J (2007). The Colony: The Harrowing True Story of the Exiles of Molokai. New York: Simon and Schuster. ISBN 978-0-7432-3301-9. Archived from the original on 2 January 2016.
  12. ↑ Hamilton, Bernard (2000). The leper king and his Heirs: Baldwin IV and the Crusader Kingdom of Jerusalem. Cambridge: Cambridge University Press. ISBN 978-0-521-64187-6.
  13. ↑ Ring, Barbra; Aubert, Elise; Winsnes, Hanna; Vogt, Johanne (1983). Aasen, Elisabeth (ed.). Fra gamle dage: memoarer, dagbøker, salmer og dikt av kvinner ca. 1660-1880 (in Norwegian). Universitetsforlaget. pp. 69–75. ISBN 8200062503.
  14. ↑ Lazatin H (8 January 2018). "5 Famous Spies Who Made Philippine History". Esquiremag.ph. Archived from the original on 22 September 2021. Retrieved 23 March 2022.
  15. ↑ Webber R (2015). Disease Selection: The Way Disease Changed the World. CABI. p. 8. ISBN 978-1-78064-682-4. Archived from the original on 8 September 2017.
  16. ↑ Cung giu Nguyên (1955). "Contemporary Vietnamese Writing". Books Abroad. 29 (1). University of Oklahoma: 19–25. doi:10.2307/40093803. JSTOR 40093803.
  17. ↑ Bryant A (1995). Sekigahara 1600: The Final Struggle for Power (Campaign Series, 40). Osprey Publishing (UK). ISBN 978-1-85532-395-7. Retrieved 28 February 2010.
  18. ↑ "Dimple Kapadia: The Bollywood actress who has overcome leprosy". The Leprosy Mission Trust India. Retrieved 2025-04-08.
  19. ↑ Fernandez, Jean (2016). "Recognizing the Leper: Hindu Myth, British Medicine, and the Crisis of Realism in Rudyard Kipling's "The Mark of the Beast"". Victorian Review. 41: 89–105. doi:10.1353/vcr.2016.0011. S2CID 164335632. Archived from the original on 2 June 2018. Retrieved 21 February 2024.
  20. ↑ "A Burnt-Out Case | novel by Greene". Encyclopedia Britannica. Archived from the original on 16 August 2021. Retrieved 16 August 2021.
  21. ↑ Squint. Archived from the original on 6 July 2022. Retrieved 20 January 2024.
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