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Metronidazole

From Wikipedia
metronidazole
type of chemical entity
Subclass ofnitroimidazole Edit
Get useMedication Edit
Stylized namemetroNIDAZOLE Edit
Chemical formulaC₆H₉N₃O₃ Edit
Canonical SMILESCC1=NC=C(N1CCO)[N+](=O)[O-] Edit
World Health Organisation international non-proprietary namemetronidazole Edit
Found insyd taxonStreptomyces hygroscopicus, Neurolaena oaxacana, Actinomadura Edit
Route of administrationoral administration, rectal administration, intravenous infusion and defusion, intravaginal administration Edit
Legal status (medicine)boxed warning Edit
Pregnancy categoryAustralian pregnancy category B2, US pregnancy category B Edit
ManufacturerPfizer Edit
WHO Aware Classificationaccess Edit

Metronidazole, dem sell under de brand name Flagyl den Metrogyl among odas, be an antibiotic den antiprotozoal medication.[1] E be used either alone anaa plus oda antibiotics to treat pelvic inflammatory disease, endocarditis, den bacterial vaginosis.[1] E be effective for dracunculiasis, giardiasis, trichomoniasis, den amebiasis.[1] E be an option for a first episode of mild-to-moderate Clostridioides difficile colitis if vancomycin anaa fidaxomicin be unavailable.[1][2] Metronidazole be available orally (by mouth), as a cream anaa gel, den by slow intravenous infusion (injection into a vein).[1][3]

Common side effects dey include nausea, a metallic taste, loss of appetite, den headaches.[1] Occasionally seizures anaa allergies to de medication fi occur.[1]

Na metronidazole begin to be commercially used insyd 1960 insyd France.[4] E be on de World Health Organization's List of Essential Medicines.[5] E be available insyd chaw areas of de world.[6] Insyd 2023, na e be de 203rd most commonly prescribed medication insyd de United States, plus more dan 2 million prescriptions.[7][8]

References

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  1. 1 2 3 4 5 6 7 "Metronidazole". The American Society of Health-System Pharmacists. Archived from the original on 6 September 2015. Retrieved 31 July 2015.
  2. ↑ McDonald LC, Gerding DN, Johnson S, Bakken JS, Carroll KC, Coffin SE, Dubberke ER, Garey KW, Gould CV, Kelly C, Loo V, Shaklee Sammons J, Sandora TJ, Wilcox MH (March 2018). "Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)". Clinical Infectious Diseases. 66 (7): e1 – e48. doi:10.1093/cid/cix1085. PMC 6018983. PMID 29462280.
  3. ↑ "Metronidazole injection, solution". DailyMed. 16 January 2023. Archived from the original on 6 September 2023. Retrieved 5 July 2023.
  4. ↑ Corey EJ (2013). Drug discovery practices, processes, and perspectives. Hoboken, N.J.: John Wiley & Sons. p. 27. ISBN 978-1-118-35446-9. Archived from the original on 8 September 2017.
  5. ↑ World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.
  6. ↑ Schmid G (28 July 2003). "Trichomoniasis treatment in women". Archived from the original on 1 August 2015. Retrieved 1 August 2015.
  7. ↑ "The Top 300 of 2023". ClinCalc. Archived from the original on 12 August 2025. Retrieved 12 August 2025.
  8. ↑ "Metronidazole Drug Usage Statistics, United States, 2013 - 2023". ClinCalc. Archived from the original on 6 December 2024. Retrieved 20 August 2025.
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