Orf (disease)
| Subclass of | skin disease, Farmyard pox, sheep disease  |
|---|---|
| Has cause | Parapoxvirus ovis |
| Health specialty | infectious diseases, veterinary medicine |
| Anatomical location | zone of skin |
| ICD-9-CM | 051.2 |
Orf be a farmyard pox, a type of zoonosis.[1] E dey cause small pustules insyd de skin of primarily sheep den goats, buh sanso fi occur on de hands of humans.[2] A pale halo dey form around a red centre.[3] E fi persist for several weeks before crusting den then either dey resolve anaa dey leave a granuloma.[3] Der be usually only one non-painful lesion, buh der fi be more.[3] Lymph nodes sanso fi cam be swollen.[3]
E be caused by a parapoxvirus.[4] E fi occur insyd humans wey dey handle infected animals anaa contaminated objects.[5] One-third of cases fi develop erythema multiforme.[3] Once resolved, a person still fi be infected again.[3]
Generally, once infected, treatment options be limited.[3] Injecting de lesion plus cidofovir anaa applying imiquimod be studied.[3] However, e sam times be required to excise de pustules.[3] De vaccine dem use insyd sheep to prevent orf be live wey e be known to cause disease insyd humans.[3]
De disease be endemic insyd livestock herds worldwide.[5] A recent outbreak emerge insyd southwest Ethiopia between October 2019 den May 2020.[5]
Orf sanso be trialed as a potential den potent viral vector vaccine platform.[6]
References
[edit | edit source]- ↑ Kassa, T (2021). "A Review on Human Orf: A Neglected Viral Zoonosis". Research and Reports in Tropical Medicine. 12: 153–172. doi:10.2147/RRTM.S306446. PMC 8275206. PMID 34267574.
- ↑ Barlow, Gavin; Irving, William L.; Moss, Peter J. (2020). "20. Infectious disease". In Feather, Adam; Randall, David; Waterhouse, Mona (eds.). Kumar and Clark's Clinical Medicine (in English) (10th ed.). Elsevier. p. 517. ISBN 978-0-7020-7870-5.
- 1 2 3 4 5 6 7 8 9 10 Petersen, Brett W.; Damon, Inger K. (2020). "348. Smallpox, monkeypox and other poxvirus infections". In Goldman, Lee; Schafer, Andrew I. (eds.). Goldman-Cecil Medicine (in English). Vol. 2 (26th ed.). Philadelphia: Elsevier. pp. 2184–2185. ISBN 978-0-323-53266-2.
- ↑ James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "19. Viral diseases". Andrews' Diseases of the Skin: Clinical Dermatology (in English) (13th ed.). Edinburgh: Elsevier. p. 389. ISBN 978-0-323-54753-6.
- 1 2 3 Kassa, T (2021). "A Review on Human Orf: A Neglected Viral Zoonosis". Research and Reports in Tropical Medicine. 12: 153–172. doi:10.2147/RRTM.S306446. PMC 8275206. PMID 34267574.
- ↑ "Prime Vector Technologies | Technology".
