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Phencyclidine

From Wikipedia
phencyclidine
type of chemical entity
Subclass ofpiperidine, phenyl compound Edit
Chemical formulaC₁₇H₂₅N Edit
Canonical SMILESC1CCC(CC1)(C2=CC=CC=C2)N3CCCCC3 Edit
World Health Organisation international non-proprietary namephencyclidine Edit
Physically dey interact plusGlutamate ionotropic receptor NMDA type subunit 2A, Glutamate ionotropic receptor NMDA type subunit 2B, Glutamate ionotropic receptor NMDA type subunit 2C, Glutamate ionotropic receptor NMDA type subunit 2D Edit
Subject has roleenzyme inhibitor, excitatory amino acid antagonist, hallucinogen, Dissociative Edit
MCN code2933.33.61 Edit

Phencyclidine anaa phenylcyclohexyl piperidine (PCP), dem sanso know insyd ein use as a street drug as angel dust among oda names, be a dissociative anesthetic dem mainly used recreationally for ein significant mind-altering effects.[1] PCP fi cause hallucinations, distorted perceptions of sounds, den psychotic behavior.[2][3] As a recreational drug, e be typically smoked, buh dem fi take am by mouth, snorted, anaa injected.[2][4] E sanso fi be mixed plus cannabis anaa tobacco.[1]

Adverse effects fi include paranoia, addiction, den an increased risk of suicide, as well as seizures den coma in cases of overdose.[2] Flashbacks fi occur despite stopping usage.[3] Chemically, PCP be a member of de arylcyclohexylamine class.[5][6] PCP dey work primarily as an NMDA receptor antagonist.[5]

PCP most commonly be used insyd de US.[7] While na usage peak insyd de US insyd de 1970s,[8] between 2005 den 2011, na an increase in visits to emergency departments as a result of de drug occur.[2] As of 2022, insyd de US, na about 0.7% of 12th-grade students report dem dey use PCP insyd de prior year, while na 1.7% of people insyd de US over age 25 report dem use am at sam point insyd dema lives.[9]

References

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  1. 1 2 "PCP Fast Facts". justice.gov. National Drug Intelligence Center. 2003. Archived from the original on 14 August 2021. Retrieved 19 February 2018.
  2. 1 2 3 4 Bush DM (2013). "Emergency Department Visits Involving Phencyclidine (PCP)". The CBHSQ Report. Rockville, MD: Substance Abuse and Mental Health Services Administration. PMID 27656747. PCP can lead to hostile behavior that may result in episodes of extreme violence
  3. 1 2 "Hallucinogens". National Institute on Drug Abuse. January 2016. Retrieved 20 February 2018.
  4. ↑ "NIDA InfoFacts: Hallucinogens – LSD, Peyote, Psilocybin, and PCP". drugabuse.gov. National Institute on Drug Abuse. Retrieved 2018-02-19.
  5. 1 2 Marion NE, Oliver WM (2014). Drugs in American Society: An Encyclopedia of History, Politics, Culture, and the Law. ABC-CLIO. p. 732. ISBN 978-1-61069-596-1 – via Google Books.
  6. ↑ Zedeck BE, Zedeck MS (2007). Forensic Pharmacology. Infobase Publishing. p. 97. ISBN 978-1-4381-0382-2.
  7. ↑ "PCP". ginad.org. Archived from the original on 2018-09-10. Retrieved 2018-02-20.
  8. ↑ "PCP". cesar.umd.edu. Archived from the original on 12 March 2010. Retrieved 20 February 2018.
  9. ↑ "Hallucinogens". drugabuse.gov. National Institute on Drug Abuse. Archived from the original on 3 June 2020. Retrieved 20 February 2018.
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