Polydactyly

polydactyly

developmental defect during embryogenesis, rare disease, class of disease

Subclass of	congenital disorder, congenital limb deformity, non-syndromic polydactyly, syndactyly and/or hyperphalangy, congenital anomaly of digit, disease
Health specialty	medical genetics
Genetic association	LMBR1, GLI3
ICD-9-CM	755.00, 755.0
ICPC 2 ID	L82
NCI Thesaurus ID	C87110

Polydactyly (dem commonly know as sixth finger den extra finger) be a birth defect wey dey result in extra fingers anaa toes. De hands be more commonly involved dan de feet. Extra fingers fi be painful, affect self-esteem, anaa result in clumsiness.

Polydactyly be associated plus at least 39 genetic mutations. E either fi be present alone anaa plus oda defects. Cases fi run insyd families. De underlying mechanism dey involve an error insyd limb bud formation during early development. Diagnosis fi occur before birth via prenatal ultrasound as early as nine weeks. X-rays fi be useful after a kiddie be a year old. De opposite be oligodactyly (fewer fingers anaa toes).

Treatment dey vary from removal by cautery to more involved surgery. While putting a tight band around de base be carried out, dis no be typically recommended. If surgery be required, dem often fi do dis around two years of age. Occasionally multiple surgeries be required.

Polydactyly be present insyd about 4 to 12 per 10,000 newborns. E be de most common defect of de hands den feet. Insyd de United States, Black people be more commonly affected dan white people. De term be Greek πολύς (polys) 'many' den δάκτυλος (daktylos) 'finger'.