Rapid eye movement sleep behavior disorder
| Subclass of | sleep disorder  |
|---|---|
| Health specialty | neurology |
| ICD-9-CM | 327.42, 780.59 |
Rapid eye movement sleep behavior disorder, anaa REM sleep behavior disorder (RBD), be a sleep disorder insyd wich people dey act out dema dreams. E dey involve abnormal behavior during de sleep phase plus rapid eye movement (REM) sleep. De major feature of RBD be loss of muscle atonia (i.e., de loss of paralysis) during otherwise intact REM sleep (during wich paralysis no be normal per buh necessary). De loss of motor inhibition dey lead to sleep behaviors wey dey range from simple limb twitches to more complex integrated movements wey fi be violent anaa result in injury to either de individual anaa dema bedmates.[1][2]
RBD be a very strong predictor of progression to a synucleinopathy (usually Parkinson's disease anaa dementia plus Lewy bodies).[3][4] Melatonin be useful insyd de treatment of RBD.[5] Na dem first describe RBD insyd 1986.
References
[edit | edit source]- ↑ St Louis EK, Boeve AR, Boeve BF (May 2017). "REM Sleep Behavior Disorder in Parkinson's Disease and Other Synucleinopathies". Mov. Disord. (Review). 32 (5): 645–658. doi:10.1002/mds.27018. PMID 28513079. S2CID 46881921.
- ↑ St Louis EK, Boeve BF (November 2017). "REM Sleep Behavior Disorder: Diagnosis, Clinical Implications, and Future Directions". Mayo Clin. Proc. (Review). 92 (11): 1723–1736. doi:10.1016/j.mayocp.2017.09.007. PMC 6095693. PMID 29101940.
- ↑ Matar E, McCarter SJ, St Louis EK, Lewis SJ (January 2021). "Current Concepts and Controversies in the Management of REM Sleep Behavior Disorder". Neurotherapeutics (Review). 18 (1): 107–123. doi:10.1007/s13311-020-00983-7. PMC 8116413. PMID 33410105.
- ↑ Arnaldi D, Antelmi E, St Louis EK, Postuma RB, Arnulf I (December 2017). "Idiopathic REM sleep behavior disorder and neurodegenerative risk: To tell or not to tell to the patient? How to minimize the risk?". Sleep Med Rev (Review). 36: 82–95. doi:10.1016/j.smrv.2016.11.002. PMID 28082168.
- ↑ Boot BP (2015). "Comprehensive treatment of dementia with Lewy bodies". Alzheimers Res Ther (Review). 7 (1) 45. doi:10.1186/s13195-015-0128-z. PMC 4448151. PMID 26029267. See lay summary from Family Practice News, April 17, 2013. Original study here.
Read further
[edit | edit source]- Roguski A, Rayment D, Whone AL, Jones MW, Rolinski M (2020). "A Neurologist's Guide to REM Sleep Behavior Disorder". Front Neurol (Review). 11: 610. doi:10.3389/fneur.2020.00610. PMC 7360679. PMID 32733361.