Rhabdomyolysis
| Subclass of | disease, myolysis  |
|---|---|
| Health specialty | emergency medicine |
| WordLift URL | http://data.medicalrecords.com/medicalrecords/healthwise/rhabdomyolysis |
| ICD-9-CM | 728.88 |
| NCI Thesaurus ID | C118318 |
Rhabdomyolysis (dem shorten as rhabdo) be a condition insyd wich damaged skeletal muscle dey break down rapidly.[1][2][3] Symptoms fi include muscle pains, weakness, vomiting, den confusion.[2][4] Der fi be tea-colored urine anaa an irregular heartbeat.[3][4] Sam of de muscle breakdown products, such as de protein myoglobin, be harmful to de kidneys den fi cause acute kidney injury.[4][5]
De muscle damage usually be caused by a crush injury, strenuous exercise, medications, anaa a substance use disorder.[4] Oda causes dey include infections, electrical injury, heat stroke, prolonged immobilization, lack of blood flow to a limb, anaa snake bites[4] as well as intense anaa prolonged exercise, particularly insyd hot conditions.[6] Statins (prescription drugs to lower cholesterol) be considered a small risk.[7] Sam people get inherited muscle conditions wey dey increase de risk of rhabdomyolysis.[4] De diagnosis be supported by a urine test strip wich be positive for "blood" buh de urine dey contain no red blood cells wen dem examine plus a microscope.[4] Blood tests dey show a creatine kinase activity greater dan 1000 U/L, plus severe disease be above 5000–15000 U/L.[3]
De mainstay of treatment be large quantities of intravenous fluids.[4] Oda treatments fi include dialysis anaa hemofiltration insyd more severe cases.[2][8] Once urine output be established, sodium bicarbonate den mannitol be commonly used buh dem be poorly supported by de evidence.[2][4] Outcomes be generally good if dem treat early.[4] Complications fi include high blood potassium, low blood calcium, disseminated intravascular coagulation, den compartment syndrome.[4]
Rhabdomyolysis be reported about 26,000 times a year insyd de United States.[4] E be a significant problem for those dem injure insyd earthquakes, den relief efforts for such disasters often dey include medical teams dem equip to treat survivors plus rhabdomyolysis.[9]
Etymology den pronunciation
[edit | edit source]De word rhabdomyolysis (/ˌræbdoʊmaɪˈɒlɪsɪs/) dey use de combining forms rhabdo- + myo- + -lysis, wey dey yield "striated muscle breakdown".
References
[edit | edit source]- ↑ "What is Rhabdo?" (in American English). National Institute for Occupational Safety and Health. 3 December 2021. Retrieved 15 December 2022.
- 1 2 3 4 Huerta-Alardín AL, Varon J, Marik PE (April 2005). "Bench-to-bedside review: Rhabdomyolysis – an overview for clinicians". Critical Care. 9 (2): 158–169. doi:10.1186/cc2978. PMC 1175909. PMID 15774072.
- 1 2 3 Chavez LO, Leon M, Einav S, Varon J (June 2016). "Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice". Critical Care. 20 (1) 135. doi:10.1186/s13054-016-1314-5. PMC 4908773. PMID 27301374.
- 1 2 3 4 5 6 7 8 9 10 11 12 Sauret JM, Marinides G, Wang GK (March 2002). "Rhabdomyolysis". American Family Physician. 65 (5): 907–912. PMID 11898964.
- ↑ Kodadek L, Carmichael Ii SP, Seshadri A, Pathak A, Hoth J, Appelbaum R, Michetti CP, Gonzalez RP (2022). "Rhabdomyolysis: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document". Trauma Surgery & Acute Care Open. 7 (1) e000836. doi:10.1136/tsaco-2021-000836. PMC 8804685. PMID 35136842.
- ↑ Oh RC, Bury DC, McClure CJ (July 2024). "Exertional rhabdomyolysis: an analysis of 321 hospitalised US military service members and its relationship with heat illness". BMJ Military Health. 170 (4): 303–307. doi:10.1136/military-2021-002028. PMID 36442890. S2CID 254067955.
- ↑ Sathasivam S, Lecky B (November 2008). "Statin induced myopathy". BMJ. 337 a2286. doi:10.1136/bmj.a2286. PMID 18988647. S2CID 3239804.
- ↑ Bosch X, Poch E, Grau JM (July 2009). "Rhabdomyolysis and acute kidney injury". The New England Journal of Medicine. 361 (1): 62–72. doi:10.1056/NEJMra0801327. PMID 19571284. S2CID 4652812.
- ↑ Vanholder R, Sever MS, Erek E, Lameire N (August 2000). "Rhabdomyolysis". Journal of the American Society of Nephrology. 11 (8): 1553–1561. doi:10.1681/ASN.V1181553. PMID 10906171.
External links
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