Irritable bowel syndrome
Subclass of | functional colonic disease, syndrome, intestinal disease, disease ![]() |
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Health specialty | gastroenterology ![]() |
Symptoms and signs | abdominal discomfort, bloating, constipation, diarrhea, abdominal pain ![]() |
Medical examination | sigmoidoscopy, colonoscopy, physical examination ![]() |
Possible treatment | diet, alkaloid, antispasmodic, β-lactulose, probiotics ![]() |
ICD-9-CM | 564.1 ![]() |
ICPC 2 ID | D93 ![]() |
NCI Thesaurus ID | C82343, C82343 ![]() |
Irritable bowel syndrome (IBS) be functional gastrointestinal disorder characterize by group of symptoms wey commonly dey include abdominal pain, abdominal bloating den changes insyd de consistency of bowel movements.[1] Dis symptoms dey occur ova long time, often years.[2] Dem classify am go four main types wey dey depend for whether diarrhea be common, constipation be common, both be common, anaa neither dey occur very often (IBS-D, IBS-C, IBS-M, anaa IBS-U respectively). IBS negatively dey affect quality of life wey go fi result for missed school anaa job.[3] Disorders lyk anxiety, major depression, den chronic fatigue syndrome be common among people plus IBS.[1][4][5]
De cause no be clear.[2] Theories dey include combinations of gut-brain axis problems, gut motility disorders, pain sensitivity, infections wey dey include small intestinal bacterial overgrowth, neurotransmitters, genetic factors, den food sensitivity.[2] Intestinal infection go fi trigger onset,[6] anaa stressful life event.[7] Insyd de latter case, dem dey bell am post-infectious irritable bowel syndrome.[6]
Dem base diagnosis for symptoms top for de absence of worrisome features wey dem rule out once oda potential conditions.[8] Worrisome features dey include onset for greater dan 50 years of age, weight loss, blood for stool insyd, anaa family history of Inflammatory bowel disease.[8] Oda conditions wey go fi be present similarly dey include celiac disease, microscopic colitis, inflammatory bowel disease, bile acid malabsorption, den colon cancer.[8]
Cure no dey; plus efforts make dem improve symptoms. Dis go fi include dietary changes, exercise, medication, probiotics, den counselling.[9][10] Dietary measures dey include increasing soluble fiber, gluten-free diet, anaa short-term diet low in fermentable oligosaccharides, disaccharides, monosaccharides, den polyols (FODMAPs). Dem go fi use de medication loperamide make e help plus diarrhea while laxatives lyk polyethylene glycol go fi help plus constipation.[8] Antidepressants, antispasmodics, den peppermint oil go fi improve overall symptoms den reduce pain.[8] Patient education den good doctor-patient relationship be important part of care.[8][11]
Dem dey believe say about 10–15% of people wey dey de developed world IBS affect.[1][12] Dem estimate say 1–45% of people globally wey IBS affect. Ebe more common for South America insyd den less common for Southeast Asia insyd.[8] Ebe twice common for women insyd as men wey edey typically occur before age 45.[1] De condition dey appear make e cam turn less common plus age.[8] IBS no dey affect life expectancy anaa dey lead go oda serious diseases.[13] Na de first description for de condition be for 1820 insyd while de current term irritable bowel syndrome cam into use for 1944 insyd.[14]
References
[edit | edit source]- ↑ 1.0 1.1 1.2 1.3 "Definition and Facts for Irritable Bowel Syndrome". NIDDKD. February 23, 2015. Archived from the original on April 2, 2016. Retrieved March 29, 2016.
- ↑ 2.0 2.1 2.2 "Symptoms and Causes of Irritable Bowel Syndrome". NIDDK. February 23, 2015. Archived from the original on April 5, 2016. Retrieved March 29, 2016.
- ↑ Hulisz D (2004). "The burden of illness of irritable bowel syndrome: current challenges and hope for the future". Journal of Managed Care Pharmacy. 10 (4): 299–309. doi:10.18553/jmcp.2004.10.4.299. PMC 10437478. PMID 15298528. S2CID 9413379.
- ↑ Whitehead WE, Palsson O, Jones KR (April 2002). "Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications?". Gastroenterology. 122 (4): 1140–56. doi:10.1053/gast.2002.32392. PMID 11910364.
- ↑ "Irritable bowel syndrome - Symptoms and causes". Mayo Clinic. Retrieved December 5, 2023.
- ↑ 6.0 6.1 Spiller R, Garsed K (May 2009). "Postinfectious irritable bowel syndrome". Gastroenterology. 136 (6): 1979–88. doi:10.1053/j.gastro.2009.02.074. PMID 19457422.
- ↑ Chang L (March 2011). "The role of stress on physiologic responses and clinical symptoms in irritable bowel syndrome". Gastroenterology. 140 (3): 761–5. doi:10.1053/j.gastro.2011.01.032. PMC 3039211. PMID 21256129.
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 8.6 8.7 Chey WD, Kurlander J, Eswaran S (March 2015). "Irritable bowel syndrome: a clinical review". JAMA. 313 (9): 949–58. doi:10.1001/jama.2015.0954. PMID 25734736. S2CID 205062386.
- ↑ "Treatment for Irritable Bowel Syndrome". NIDDK. February 23, 2015. Archived from the original on April 6, 2016. Retrieved March 29, 2016.
- ↑ Palsson OS, Peery A, Seitzberg D, Amundsen ID, McConnell B, Simrén M (December 2020). "Human Milk Oligosaccharides Support Normal Bowel Function and Improve Symptoms of Irritable Bowel Syndrome: A Multicenter, Open-Label Trial". Clinical and Translational Gastroenterology. 11 (12): e00276. doi:10.14309/ctg.0000000000000276. PMC 7721220. PMID 33512807.
- ↑ Mayer EA (April 2008). "Clinical practice. Irritable bowel syndrome". The New England Journal of Medicine. 358 (16): 1692–1699. doi:10.1056/NEJMcp0801447. PMC 3816529. PMID 18420501.
- ↑ Maxion-Bergemann S, Thielecke F, Abel F, Bergemann R (2006). "Costs of irritable bowel syndrome in the UK and US". PharmacoEconomics. 24 (1): 21–37. doi:10.2165/00019053-200624010-00002. PMID 16445300. S2CID 45376327.
- ↑ Quigley EM (2013). "Treatment level 1". Irritable Bowel Syndrome: Diagnosis and Clinical Management (First ed.). Chichester, West Sussex: Wiley-Blackwell. ISBN 978-1-118-44474-0. Archived from the original on September 8, 2017.
- ↑ Hatch MC (2000). Women and Health. San Diego, Calif: Academic Press. p. 1098. ISBN 978-0-12-288145-9. Archived from the original on September 8, 2017.
External links
[edit | edit source]Wikimedia Commons get media wey relate to Irritable bowel syndrome.
- Irritable bowel syndrome at Curlie